Primary adrenal insufficiency
https://doi.org/10.30629/0023-2149-2024-102-3-264-267
Abstract
Due to the non-specificity of a number of clinical manifestations of Addison’s disease, the diagnosis of primary adrenal insufficiency in general therapeutic profile hospitals causes certain difficulties. The article presents a clinical case of diagnosing primary adrenal insufficiency in combination with autoimmune thyroiditis and hypogonadism as a manifestation of autoimmune polyglandular syndrome. Signs of Addison’s disease included hyperpigmentation of the skin and mucous membranes of the oral cavity, as well as low cortisol levels and an increase in adrenocorticotropic hormone(ACTH) concentration, detected in the blood serum antibodies to thyroperoxidase — a specific marker of autoimmune thyroid gland damage. A positive result of the test for autoantibodies to steroid-producing cells indicated functional ovarian insufficiency.
About the Authors
T. I. Kalenchits
Belarusian State Medical University
Belarus
Belarus
Tamara I. Kalenchits — Сand. of Sci. (Med.), Associate Professor, Department of Medical Rehabilitation and Physiotherapy
Minsk
S. L. Kabak
Belarusian State Medical University
Belarus
Belarus
Sergey L. Kabak — Dr of Sci. (Med.), Professor, Head of the Human Morphology Department
Minsk
N. S. Didenko
Bakoulev National Medical Research Center for Cardiovascular Surgery of the Ministry of Healthcare of Russia, Rehabilitation Сenter for Сhildren with Heart Defects
Russian Federation
Russian Federation
Natalia S. Didenko — MD, Department of Functional Diagnostics
Moscow
I. V. Glushko
6th City clinical hospital
Belarus
Belarus
Inessa V. Glushko — MD, Head of the Cardiology Department
Minsk
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Review
For citations:
Kalenchits T.I., Kabak S.L., Didenko N.S., Glushko I.V. Primary adrenal insufficiency. Clinical Medicine (Russian Journal). 2024;102(3):264-267. (In Russ.) https://doi.org/10.30629/0023-2149-2024-102-3-264-267
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