Diagnosis and prognosis of myocardial infarction in the elderly by informative cardiomarkers
https://doi.org/10.30629/0023-2149-2020-98-4-282-286
Abstract
Myocardial infarction in old age is the leading pathology and cause of deaths.
The aim of the study was to evaluate the prognostic signif cance and informative value of cardiac markers of blood in elderly patients with myocardial infarction.
Material and methods. The study of cardiac markers in 107 patients with myocardial infarction at the age of 65--75 years and in 83 patients with myocardial infarction at the age of 50-60 years was carried out by immunochromatographic, bioluminescent methods and by electrophoresis on cellulose acetate, followed by the calculation of informativeness and prognostic coefficients. 95 persons aged 65-75 years without myocardial infarction served as control.
Results. Troponin T, brain natriuretic peptide, glucose-6-phosphate dehydrogenase and lactate dehydrogenase-1 have the most informative and prognostic signif cance in elderly patients with myocardial infarction.
Conclusion. The use of these cardiac markers will improve the diagnosis and isolation of patients with myocardial infarction at high risk.
About the Authors
N. M. Agarkov
Southwestern State University
Russian Federation
Russian Federation
Nikolay M. Agarkov — MD, PhD, DSc, prof. of biomedical engineering Department, Southwestern state University.
305040, Kursk.
M. Yu. Markelov
Information and Methodological Center for Examination Accounting and Analysis of Medical Devices
Russian Federation
Russian Federation
109074, Moscow.
E. A. Markelova
Information and Methodological Center for Examination Accounting and Analysis of Medical Devices
Russian Federation
Russian Federation
109074, Moscow.
P. S. Volkov
JSC «Russian Railways» Scientific Clinical Center
Russian Federation
Russian Federation
125367, Moscow.
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Review
For citations:
Agarkov N.M., Markelov M.Yu., Markelova E.A., Volkov P.S. Diagnosis and prognosis of myocardial infarction in the elderly by informative cardiomarkers. Clinical Medicine (Russian Journal). 2020;98(4):282-286. (In Russ.) https://doi.org/10.30629/0023-2149-2020-98-4-282-286
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