Возрастные изменения системы гемостаза
https://doi.org/10.34651/0023-2149-2020-98-1-9-12
Аннотация
Инфаркт миокарда, инсульт и венозный тромбоэмболизм, в основе которых лежит тромбоз сосудов, являются ведущими причинами смерти населения. Наиболее часто эти заболевания развиваются при старении организма человека. С возрастом происходят такие изменения в системе гемокоагуляции, как повышение уровня фибриногена, факторов VIII и IX и других прокоагулянтов без пропорционального увеличения количества антикоагулянтных факторов, уменьшение количества тромбоцитов и повышение их активности, снижение активности фибринолиза, развивается эндотелиальная дисфункция. Все это приводит к повышению интенсивности внутрисосудистого свертывания крови и развитию тромбозов.
Об авторах
Е. В. Крюков
ФГБУ «Главный военный клинический госпиталь им. акад. Н.Н. Бурденко» Министерства обороны России
Россия
Россия
Крюков Евгений Владимирович — д-р мед. наук, проф., член-корр. РАН, начальник госпиталя
105094, Москва
SPIN: 3900-3441
Т. С. Паневин
ФГБУ «Главный военный клинический госпиталь им. акад. Н.Н. Бурденко» Министерства обороны России
Россия
Россия
105094, Москва
SPIN-код: 7839-3145
Л. В. Попова
ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» (Сеченовский Университет) Минздрава России
Россия
Россия
119991, Москва
SPIN-код: 1251-9273
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Рецензия
Для цитирования:
Крюков Е.В., Паневин Т.С., Попова Л.В. Возрастные изменения системы гемостаза. Клиническая медицина. 2020;98(1):9-12. https://doi.org/10.34651/0023-2149-2020-98-1-9-12
For citation:
Kryukov E.V., Panevin T.S., Popova L.V. Age-related changes in the hemostasis system. Clinical Medicine (Russian Journal). 2020;98(1):9-12. (In Russ.) https://doi.org/10.34651/0023-2149-2020-98-1-9-12
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