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Features of the course of the new coronavirus infection in patients with bronchial asthma and allergic reactions

https://doi.org/10.30629/0023-2149-2025-103-12-885-892

Abstract

The high pathogenicity of SARS-CoV-2 and the airborne transmission mechanism are a public health concern. At first, it was believed that a history of allergic reactions aggravated the course of the disease. Later, it turned out that bronchial asthma (BA) in patients or other allergic diseases did not affect the severity of coronavirus infection (CVI).

Objective. The aim of the study is to identify the relationship between the course of COVID-19 in patients with asthma and allergies.

Material and methods. As a result of the cross-sectional study of the hypothesis, a retrospective analysis of people was conducted for the years 2019–2023. The study group — patients with confirmed COVID-19 and the presence of dispensary registration for bronchial asthma, patients with confirmed COVID-19 and a history of allergies. To assess the severity of the disease, laboratory parameters of patients in dynamics and symptoms were taken.

Results. Women with COVID-19 have lower ESR levels than women with concomitant asthma and allergies; men have identical results. The CRP indicators in women with an aggravated anamnesis increase sharply, in contrast to individuals with COVID-19. In men, no significant differences in the CRP results were found.

Conclusion. In women and men with bronchial asthma and/or a history of allergies, the course of COVID-19 was milder, both according to laboratory data and the corresponding clinical picture.

About the Authors

A. S. Tambovskaya
Tula State University
Russian Federation

Anastasia S. Tambovskaya — 6th year student 

Tula 



V. A. Klyukina
Tula State University
Russian Federation

Valeria A. Klyukina — 6th year student  

Tula 



S. G. Nekhaev
Tula State University
Russian Federation

Sergey G. Nekhaev — Candidate of Medical Sciences, Associate Professor of the Department of Infectious Diseases

Tula 



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Review

For citations:


Tambovskaya A.S., Klyukina V.A., Nekhaev S.G. Features of the course of the new coronavirus infection in patients with bronchial asthma and allergic reactions. Clinical Medicine (Russian Journal). 2025;103(12):885-892. (In Russ.) https://doi.org/10.30629/0023-2149-2025-103-12-885-892

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ISSN 0023-2149 (Print)
ISSN 2412-1339 (Online)