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Modern approaches to the choice of schemes for eradication of Helicobacter рylori infection (based on the materials of the consensus meeting "Maastricht-VI")

https://doi.org/10.30629/0023-2149-2023-101-11-582-587

Abstract

The article presents an analysis of the provisions of the consensus meeting “Maastricht-VI”, dedicated to the treatment  of Helicobacter pylori (H. pylori) infection. The expediency of preliminary testing for H. pylori sensitivity to antibiotics is emphasized. Since this strategy has not yet been implemented in everyday clinical practice, empirical therapy is often carried  out based on the results of the assessment of H. pylori resistance to antibiotics in this region. The sequence of administration of  eradication regimens of the 1st, 2nd, 3rd, 4th lines, optimal duration of treatment, new therapy regimens (with rifabutin, double  therapy with proton pump inhibitors and amoxicillin in high doses) are considered. The implementation of the new consensus  meeting will contribute to improving the results of eradication therapy of H. pylori infection.

About the Authors

A. A. Sheptulin
I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russia (Sechenov University)
Russian Federation

Sheptulin Arkady A.

119991, Moscow



S. S. Kardasheva
I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russia (Sechenov University)
Russian Federation

Kardasheva Svetlana S.

119991, Moscow



A. A. Kurbatova
I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russia (Sechenov University)
Russian Federation

Kurbatova Anastasia A.

119991, Moscow



References

1. Malfertheiner P., Megraud F., O’Morain C.A., Gisbert J.P., Kuipers E.J., Axon A.T. et al. Management of Helicobacter pylori infection — the Maastricht V/Florence consensus report. Gut. 2017;66(1):6–30. DOI: 10.1136/gutjnl-2016-312288

2. Malfertheiner P., Megraud F., Rokkas T., Gisbert J.P., Liou I.-M., Schulz C. et al. Management of Helicobacter pylori infection: the Maastricht VI/Florence consensus report. Gut. 2022;0:1–39. Epub ahead. DOI: 10.1136/gutjnl-2022-3277451


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For citations:


Sheptulin A.A., Kardasheva S.S., Kurbatova A.A. Modern approaches to the choice of schemes for eradication of Helicobacter рylori infection (based on the materials of the consensus meeting "Maastricht-VI"). Clinical Medicine (Russian Journal). 2023;101(11):582-587. (In Russ.) https://doi.org/10.30629/0023-2149-2023-101-11-582-587

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ISSN 0023-2149 (Print)
ISSN 2412-1339 (Online)