Granulomatosis with polyangiitis
https://doi.org/10.30629/0023-2149-2020-98-5-378-382
Abstract
Granulomatosis with polyangiitis is necrotizing vasculitis of small vessels and much less often aff ected vessels of medium caliber with the involvement of the respiratory tract and kidneys. It can occur under a variety of masks, not only in the debut, but also in the period of intensive clinical picture, making it diffi cult to diagnose and aff ects the prognosis of life. The article describes a clinical case of Wegener’s granulomatosis in a patient of 68 years, proceeding with damage to the lungs, kidneys and the further development of respiratory and renal failure.
About the Authors
S. A. Shchekina
Medical Institute of the N.Р. Ogarev National Research Mordovian State University
Russian Federation
Russian Federation
Svetlana A. Shchekina — student
430032, Saransk
L. A. Balykova
Medical Institute of the N.Р. Ogarev National Research Mordovian State University
Russian Federation
430032, Saransk
Russian Federation
430032, Saransk
N. M. Selezneva
Medical Institute of the N.Р. Ogarev National Research Mordovian State University
Russian Federation
Russian Federation
430032, Saransk
References
1. Chuchalin A. G. Respiratory medicine: manual in 3 vols. 2nd ed., re-ed. and add. M.: Letterra, 2017; Т. 2. 544 с.
2. Greco A., Marinelli C., Fusconi M. et al. Clinic manifestations in granulomatosis with polyangiitis. Int. J. Immunopathol. Pharmacol. 2016;29(2):151–9.
3. Pérez-Jacoiste Asín M.A, Charles P., Rothschild P.R., Terrier B., Brézin A., Mouthon L., Guillevin L., Puéchal X. Ocular involvement in granulomatosis with polyangiitis: A single-center cohort study on 63 patients. Autoimmun. Rev. 2019 Mar 4.
4. Catanoso M., Macchioni P., Boiardi L. et al. Epidemiology of granulomatosis with polyangiitis (Wegener’s granulomatosis) in Northern Italy: a 15-year population-based study. Semin. Arthritis Rheum. 2014;44(2):202–7.
5. Weiner M., Segelmark M. The clinical presentation and therapy of diseases related to anti-neutrophil cytoplasmic antibodies (ANCA). Autoimmunity Reviews. 2016;15(10):978–982.
6. Tarabishy A.B., Schulte M., Papaliodis G.N., Hoff man G.S. Wegener’s granulomatosis: clinical manifestations, diff erential diagnosis, and management of ocular and systemic disease. Surv Ophthalmol. 2014;55(5):429–44.
7. Parperis K., Abdulqader Y. Aortitis and pachymeningitis: an unusual combination in granulomatsis with polyangiitis (myeloperoxidase associated vasculitis). BMJ Case Rep. 2019 Jan 28;12(1).
8. Tóth I., Kaszás B., Horváth G., Piski Z., Bakó P., Lujber L., Gerlinger I., Révész P. Modern management of otologic consequences of Wegener’s granulomatosis — a case report and review of the literature. Orv. Hetil. 2019 Jan;160(4):151–157.
Review
For citations:
Shchekina S.A., Balykova L.A., Selezneva N.M. Granulomatosis with polyangiitis. Clinical Medicine (Russian Journal). 2020;98(5):378-382. (In Russ.) https://doi.org/10.30629/0023-2149-2020-98-5-378-382
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