Сauses, risk factors, diagnostics and treatment of gastrointestinal bleeding in patients with a novel coronavirus infection (COVID-19)
https://doi.org/10.30629/0023-2149-2022-100-7-8-341-345
Abstract
The article discusses the pathogenetic and clinical aspects of gastrointestinal bleeding (GIB) in patients with a novel coronavirus infection (COVID-19). The possibility of direct interaction of the coronavirus with the receptors of the angiotensinconverting enzyme 2 (ACE-2) of the mucous membrane of the gastrointestinal tract with the development of its damage and subsequent bleeding has been shown. The value of anticoagulant therapy as a risk factor for the occurrence of GIB is evaluated inconsistently. In most patients with COVID-19 infection and GIB conservative hemostatic therapy is eff ective. The infl uence of GIB on the course and prognosis of a novel coronavirus infection has an contradictory interpretation. Given the lack of knowledge of the pathogenetic and clinical aspects of GIB in patients with COVID-19 infection, this problem requires further research.
About the Authors
A. A. Sheptulin
I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation
Russian Federation
Sheptulin Arkadiy A.
119991, Moscow
S. S. Kardasheva
I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation
Russian Federation
Kardasheva Svetlana S.
119991, Moscow
A. A. Kurbatova
I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation
Russian Federation
Kurbatova Anastasia A.
119991, Moscow
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Review
For citations:
Sheptulin A.A., Kardasheva S.S., Kurbatova A.A. Сauses, risk factors, diagnostics and treatment of gastrointestinal bleeding in patients with a novel coronavirus infection (COVID-19). Clinical Medicine (Russian Journal). 2022;100(7-8):341-345. (In Russ.) https://doi.org/10.30629/0023-2149-2022-100-7-8-341-345
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