Preview

Clinical Medicine (Russian Journal)

Advanced search

Modern approaches to solving the problem of comorbidity

https://doi.org/10.30629/0023-2149-2022-100-1-57-62

Abstract

The article presents a model of comorbidity, which is designed to identify the general patterns of the formation of combined pathology, the features of the methodology of its detection and the general principles of therapy. In order to unify approaches to the diagnosis and treatment of comorbid conditions, the outcome of which is the formation of tissue and organ sclerosis, the concept of chronic sclerotic disease (CSD) is proposed. The proposed methodology and techniques, as well as the data obtained with their help, determine the ability to identify risk groups, plan the direction and scope of the examination, draw up a plan for the necessary point therapeutic effects in patients with CSD, which, in turn, can lead to increased effectiveness of preventive and therapeutic measures in comorbidity.

About the Authors

Ya. A. Kats
Saratov State Medical University named after V. I. Razumovsky of the Ministry of Healthcare of Russian Federation
Russian Federation

Kats Yakov Alexandrovich

410012, Saratov



E. V. Parkhoniuk
Saratov State Medical University named after V. I. Razumovsky of the Ministry of Healthcare of Russian Federation
Russian Federation

Parkhoniuk Elena Vladimirovna

410012, Saratov



S. A. Skriptsova
Saratov State Medical University named after V. I. Razumovsky of the Ministry of Healthcare of Russian Federation
Russian Federation

Skriptsova Sofia Anatolyevna

410012, Saratov



References

1. Feinstain A.R. Pre-therapeutic classification of comorbidity in chronic disease. Journal of Chronic Diseases. 1970;23(7):455–468. DOI: 10.1016/0021-9681(70)90054-8

2. Krohn W., Küppers Gunter, Nowotny H. Selforganization — the convergence of ideas in intrudaction. Selforganization: portrait of a scientific revolution. Springer Science+Business Media B.V. 1990;1–10. DOI: 10.1007/978-94-017-2975-8

3. Novikov D.A. Cybernetics: Navigator. History of cybernetics, current state, development prospects. Moscow: LENAND, 2016.160. (In Russian)]. URL: http://www.methodolog.ru/books/kiber.pdf

4. Kats Y.A., Parkhoniuk E.V. Periods and phases of the disease in the view of predictive preventive medicine. The meaning and principles of integrative diagnostics. Klinicheskaya meditsina. 2013;6:75–77. (In Russian)]. URL: https://cyberleninka.ru/article/n/periody-i-fazybolezni-v-svete-prediktivnopreventivnoy-meditsiny-znachenie-iprintsipy-integrativnoy-diagnostiki/viewer

5. Ardamatsky N.A. Introduction to general therapy: Aspects of the methodology of medical work. Monographia. Saratov: Izdatelstvo Saratovskogo meditsinskogo universiteta, 1991:304. (In Russian)

6. Anokhin P.K. Essays on the physiology of functional systems. P.K. Anokhin. Moscow: Meditsina, 1975:447. (In Russian)

7. Kats Y.A. Diagnostics: fundamentals of theory and practice. Monographia. Saratov: Izdatelstvo Saratovskogo meditsinskogo universiteta, 2012:357. (In Russian)

8. Anokhin P.K. Methodological significance of cybernetic patterns. In: Materialistic Dialectics and Methods of Natural Sciences. Moscow: Nauka, 1968:578. (In Russian). URL: https://www.keldysh.ru/pages/BioCyber/RT/Functional.pdf

9. Kats Y.A., Parkhoniuk E.V., Akimova N.S., Korsunova E.N., Skriptsova S.A Sclerosis and functional systems of the body. Fundamentalnye issledovaniya. 2014;7(4):711–718. (In Russian). URL: https://fundamental-research.ru/ru/article/view?id=34966 (дата обращения: 28.10.2021)

10. Valenkevich L.N., Yakhontova O.I. Non-cirrhotic liver fibrosis. Rossiysky gastroenterologicheskiy jurnal. 2000;4:21–23. (In Russian). URL: https://medi.ru/info/12546/

11. Kirichuk V.F., Chorovodov A.Y., Zheleznikova N.A., Shvarts Yu.G. Heart rate variability and platelet functional activity in patients with atrial fibrillation. Vestnik aritmologii. 2002;30:39–42. (In Russian)

12. Kats Y.A., Parkhoniuk E.V., Skriptsova S.A. Sclerotic disease, integrative diagnostics and ways to solve the problems of chronization and treatment of diseases. Saratov Journal of Medical Scientific Research. 2015;11(3):268– 274. (In Russian). URL: https://www.ssmj.ru/system/files/2015_03_268-274.pdf

13. Kats Y.A., Parkhoniuk E.V. Sclerosis: local and general mechanisms of development. Klinicheskaya meditsina. 2015;8:29–38. (In Russian)

14. Shutov A.M. Chronic kidney disease is a global problem of the XXI century. Klinicheskaya meditsina. 2014;5:5–10. (In Russian). URL: https://cyberleninka.ru/article/n/hronicheskaya-bolezn-pochek-globalnayaproblema-xxi-veka

15. Kats Y.A., Parkhoniuk E.V., Korsu nova E.N., Skriptsova S.A. Chronic sclerotic disease. Modern problems of Science and Education. 2015;1(1). (In Russian). URL: https://science-education.ru/ru/article/view?id=19162 (дата обращения: 28.10.2021)

16. Kats Y.A., Skriptsova S.A. Evolution of comorbid conditions and the concept of chronic sclerotic disease. Х National congress of internists. 2015:78. (In Russian). URL: https://congress.rnmot.ru/public/files/events/2/261/Cover_tez_NKT.pdf

17. Kats Y.A. Integratism as a methodological basis for studying the pathology of internal organs. Allergy, immunity and pathology of internal organs: Sbornik nauchnyh trudov. Ryazan, 1995:58. (In Russian)

18. Kats Y.A. Arterial hypertension, connective tissue dysplasia, atherosclerosis, systemic connective tissue diseases and a single biochemical and morphological substrate of diseases. Materials of the 9th All-Russian Scientific and Educational Forum «Cardiology 2007». Moscow, 2007:124–125. (In Russian)]. URL: https://www.mediexpo.ru/fileadmin/user_upload/content/pdf/thesis/thesis_car_07.pdf

19. Sudakov K.V. Normal Physiology: A textbook for medical students. Moscow: Meditsinskoe informatsionnoe agenstvo, 2006:919. (In Russian)

20. Fridman S. Mechanisms of disease: mechanisms of hepatic fibrosis andtherapeutic implications. Nat. Clin. Prac. Gastroenterol. Hepatol. 2004;1(2):98–105. DOI: 10.1038/ncpgasthep0055

21. Pav lov Ch.S, Ivashkin V.T.,Shulpecova Y.O., Zolotarevskiy V.B. Modern ideas about the pathogenesis, diagnosis and treatment of liver fibrosis. Russian Journal of gastroenterology, hepatology, coloproctology. 2005;2:13–20. (In Russian)

22. Bestaev D.V., Karataev D.E., Nasonov E.L. Tactics of mana gement of patients with pulmonary fibrosis. Klinicheskaya meditsina. 2014;92(2):17–23. (In Russian). URL: https://cyberleninka.ru/article/n/taktika-vedeniya-bolnyh-s-fibrozom-legkih/viewer

23. Rockey D.C. Antifibrotic therapy in chronic liver disease. Clin. Gastroenterol. Hepatol. 2005;3(2):95–107. (In Russian)]. DOI: 10.1016/s1542-3565(04)00445-8.


Review

For citations:


Kats Ya.A., Parkhoniuk E.V., Skriptsova S.A. Modern approaches to solving the problem of comorbidity. Clinical Medicine (Russian Journal). 2022;100(1):57-62. (In Russ.) https://doi.org/10.30629/0023-2149-2022-100-1-57-62

Views: 625


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 0023-2149 (Print)
ISSN 2412-1339 (Online)