The prevalence of agerelated hypogonadism in employed middle-aged men and its relationship with cardiovascular risk factors

The prevalence of age-related diseases, including age-related hypogonadism in men, have increased with improved life
expectancy of the population. This study is aimed at assessing the prevalence of age-related hypogonadism in healthy working middle-aged men and determining the relationships with cardiovascular risk factors.
Material and methods. Men who underwent annual medical examinations were additionally questioned to identify symptoms of age-related hypogonadism. Level of sex and gonadotropic hormones were measured in the study sample. Cardiovascular risk factors and cardiac risk were estimated in all recruited subjects.
Results. Age-related hypogonadism was diagnosed in 35 (32,1%) men. The prevalence of cardiovascular risk factors such as obesity, metabolic syndrome, and depression was significantly higher among men with age-related hypogonadism compared with men with normal testosterone levels.
Conclusion. Early diagnosis and treatment of age-related hypogonadism in middle-aged men is relevant for improving their quality of life and managing cardiovascular risk factors, thereby increasing the effectiveness of primary prevention of cardiovascular morbidity and mortality. When agerelated hypogonadism is diagnosed, optimal management strategy should be selected. The identified cardiovascular risk factors should be modified using a more aggressive approach.

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