The structure of anemia in geriatric patients of therapeutic and surgical profile
https://doi.org/10.30629/0023-2149-2025-103-12-907-912
Abstract
Objective: the study objective is to identify etiological factors and pathogenetic mechanisms of anemia development in geriatric patients hospitalized in therapeutic and surgical departments.
Material and methods. А retrospective analysis of 415 elderly, senile and long-lived patients hospitalized in the therapeutic departments, urological and gynecological departments of the Irkutsk Regional Clinical Hospital, who were diagnosed with anemia during the examination, was carried out.
Results. An analysis of medical records showed that 3,632 patients over the age of 60 were treated in the departments. The incidence of anemia was 11.4% among all hospitalized patients over the age of 60. Of the examined patients, women predominated in 61% of cases. Anemia of mild severity was diagnosed in 50% of patients. Anemia of chronic diseases prevailed in the structure of anemia and was diagnosed in 208 (50%) patients, iron deficiency anemia was detected in 91 (22%) patients.
Conclusions. Thus, as a result of the study, the structure of anemia was revealed in elderly, senile and long-lived patients hospitalized at the Irkutsk Regional Clinical Hospital. The high prevalence of anemia of chronic diseases in this age group was revealed, due to the comorbidity of geriatric patients and the multifactorial genesis of anemia. The above causes the difficulty of diagnosing anemia in patients over 60 years of age.
About the Authors
A. A. RyshchukRussian Federation
Anastasia A. Ryshchuk — hematologist
Irkutsk
О. А. Rukavitsyn
Russian Federation
Оleg А. Rukavitsyn — Doctor of Medical Sciences, Professor, Chief Hematologist of the Russian Ministry of Defense, Head of the Hematology Center
Moscow
N. O. Saraeva
Russian Federation
Natalya O. Saraeva — Doctor of Medical Sciences, Professor of the Department of Hospital Therapy, Chief freelance specialist hematologist of the Ministry of Health of the Irkutsk Region
Irkutsk
References
1. Anemia. O.A. Rukavitsin [ed.]. 2nd revised edition. Moscow: GEOTARMedia, 2021:352. (In Russian). DOI: 10.33029/9704-6293-5-ANM-2021-1-352
2. Goodnough L.T., Schrier S.L. Evaluation and management of anemia in the elderly. American Journal of Hematology. 2014;89(1):88–96. DOI: 10.1002/ajh.23598
3. Bross M.N., Soch K., Smith-Knuppel. Anemia in older persons. American Family Physician. 2010;82 (5):480–487. URL: https://www.aafp.org/pubs/afp/isues/2010/0901/p480.html.
4. Gaskell H., Derry S., Andrew Moore R. Prevalence of anaemia in older persons: systematic review. BMC Geriatrics. 2008;14(8):1. DOI: 10.1186/1471 2318–8–1
5. Stauder R., Thein S. L. Anemia in the elderly: clinical implications and new therapeutic concepts. Haematologica. 2014;99(7): 1127– 1130. DOI: 10.3324/haematol.2014.109967
6. DenElzen W.P.J., Gussekloo J. Anaemia in older person. Netherlands journal of. medicine. 2011;69(6):260–267. URL: https://hdl.handle.net/1887/117602
7. Merchant A.A., Roy C.N. Not so benign haematology: anaemia of the elderly. British journal of haematology. 2012;156 (2):173–185. DOI: 10.1111/j.1365-2141.2011.08920.x
8. Beerman I., Bhattacharya D., Zandi S. et al. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc. Nat. Acad. Sci. USA. 2010;107 (12):5465–5470. DOI: 10.1073/pnas.1000834107
9. Den Elzen W. P. J., Martin-Ruiz C., von Zglinicki T. Telomere length and anaemia in old age: results from the Newcastle 85-plus Study and the Leiden 85-plus Study. Age and аgeing. 2011;40(4):494–500. DOI 10.1093/ageing/afr048.
10. Bogdanov A.N., Voloshin S. V. Anemia in the elderly and senile age. The Bulletin of Hematology. 2021;1:47–66. (In Russian). URL: https://bloodscience.ru/wpcontent/uploads/2023/05/1_21.pdf
11. Ausk K.J., Ioannou G.N. Is obesity associated with anemia of chronic disease? A population-based study. Obesity (Silver Spring). 2008;16:2356–2361. DOI 10.1038/oby.2008.353
12. Bayne S., Jones M.E., Li H., Liu J.P. Potential roles for estrogen in regulation of telomerase activity in aging. Ann. NY Acad. Scienc. 2007;114:48–55. DOI: 10.1196/annals.1396.023.Ferrucci L., Maggio M., Longo D. L. Low testosterone levels and the risk of anemia in older men and women. Arch. Int. Med. 2006;166(13):1380– 1388. DOI: 10.1001/archinte.166. 13.1380
13. Sakhin V.T., Madzhanova E.R., Kryukov E.V., Sotnikov A.V., Gordienko A.V., Rukavitsyn O.A. Pathogenetic Characteristics of Anemia in Patients with Solid Tumors. Clinical oncohematology. 2017;10(4):514– 519. (In Russian). URL: https://old.bloodjournal.ru/wp-content/uloads/2017/10/11_1.pdf?ysclid=lvo21iypd7994236993
14. Valent P., Orazi A., Steensma D. P. et al. Proposed minimal diagnostic criteria for myelodysplastic syndromes (MDS) and potential preMDS conditions. Oncotarget. 2017;8 (43):73483–73500. DOI: 10.18632/oncotarget.19008
15. Frangos E. Malnutrition in very old hospitalized patients: A new etiologic factor of anemia? J. Nutr. Heal. Aging. 2016;20(7):705– 713. DOI: 10.1007/ s12603-015-0641-6
16. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity, Vitamin and Mineral Nutrition Information System. Geneva, World Health Organization, 2011. URL: https://www.who.int/publications/i/item/WHO-NMH-NHD-MNM-11.1
17. Van Santen S., Van Dongen-Lases E.C., de Vegt F. et al. Hepcidin and hemoglobin content parameters in the diagnosis of iron defi - ciency in rheumatoid arthritis patients with anemia. Arthritis Rheum. 2011;63(12):3672–3680. DOI: 10.1002/art.30623
18. Worwood M., May A.М. Bain B.J. Iron deficiency anemia and iron overload. Dacie and Lewis Practical Haematology. 2017;9:165–186. DOI: 10.1016/b978-0-7020-6696-2.00009-6
19. Moiseev SV. Capacities of somatostatin analogues to treat castration-resistant prostate cancer. P.A. Herzen Journal of Oncology. 2012;1(1):77– 82. (In Russian). URL: https://www.mediasphera.ru/issues/onkologiya-zhurnal-im-p-a-gertsena/2012/1/03102899842012119?ysclid=lvo2x387zw387879363
20. Merchant A.A., Roy C.N. Not so benign haematology: anaemia of the elderly. Br. J. Haematol. 2012;156(2):173–185. DOI: 10.1111/j.1365-2141.2011.08920.x Epub 2011 Nov 3.
21. Michalak S.S., Rupa-Matysek J., Gil L. Como bidities, repeated hospitalizations, and age ≥80 years as indicators of anemia development in the older population. Ann. Hematol. 2018;97(8): 1337–1347. DOI: 10.1007/s00277-018-3321-x
22. Schop A. A new diagnostic work-up for defining anemia etiologies: a cohort study in patients ≥50 years in general practices. BMC Fam. Pract. 2020;21(1):167. DOI: 10.1186/s12875-020-01241-7
23. Patel K.V., Longo D.L., Guralnik J.M. Hemoglobin concentration and the risk of death in older adults: differences by race/ethnicity in the NHANES III Follow-up. Brit. J. Haematol. 2009;145 (94):514– 523. DOI: 10.1111/j.1365-2141.2009.07659x
24. Socha D.S., DeSouza S.I., Flagg A. et al. Severe megaloblastic anemia: Vitamin deficiency and other causes. Cleveland Clinic Journal of Medicine. 2020;87(3):153–164. DOI: 10.3949/ccjm.87a.19072
25. Lukina E.A., Тsvetaeva N.V., Dvirnyk V.N. B12-deficiency anemia. Clinical recommendations. 2020:28. (In Russian). URL: https://webmed.irkutsk.ru/doc/pdf/kr536.pdf
Review
For citations:
Ryshchuk A.A., Rukavitsyn О.А., Saraeva N.O. The structure of anemia in geriatric patients of therapeutic and surgical profile. Clinical Medicine (Russian Journal). 2025;103(12):907-912. (In Russ.) https://doi.org/10.30629/0023-2149-2025-103-12-907-912
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