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Analysis of the causes of chordal rupture and its connection with comorbid states
https://doi.org/10.30629/0023-2149-2025-103-10-11-814-819
Abstract
Background. Chordal rupture is a rare complication of various diseases and conditions, occurring both primary and secondary. This condition can lead to acute mitral regurgitation and death of the patient, it is necessary to keep in mind a number of diseases and conditions that can cause this complication or be a risk factor. Purposes. It nesessary to analyze the causes of tendon chord detachment, identify the most frequent and the rarest of them. Determine the association of comorbidities with tendon chord detachment. Material and methods. Literature data were summarized and analyzed. Literature search was carried out in Scopus and Pubmed databases. Conclusions. Chordal rupture remains a complication of a large number of diseases. At present, chordal rupture occurs predominantly as a complication of degenerative mitral valve diseases in elderly patients, which correlates with the global trend. The role of rheumatic heart disease and infectious endocarditis as causes of chordal rupture has decreased, but still remains significant.
About the Authors
E. I. Dedov
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Evgeniy I. Dedov — Doctor of Medical Sciences, Associate Professor, Professor of the Department of Hospital Therapy No. 2 of the Medical Faculty, Russian National Research Medical University named after N.I. Pirogov.
Moscow
A. A. Kraineva
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Anna A. Kraineva — Resident of the Cardiology Department with a Course in Arrhythmology and Interventional Methods of Diagnosis and Treatment, Federal State Institution National Medical Research Center for therapy and Preventive Medicine of the Ministry of Healthcare of the Russian Federation.
Moscow
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For citations:
Dedov E.I., Kraineva A.A. Analysis of the causes of chordal rupture and its connection with comorbid states. Clinical Medicine (Russian Journal). 2025;103(10-11):814-819. (In Russ.) https://doi.org/10.30629/0023-2149-2025-103-10-11-814-819
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