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Disorders of ventilatory function in patients with mycobacteriosis
https://doi.org/10.30629/0023-2149-2025-103-3-202-207
Abstract
The aim of this study was to investigate the nature and frequency of functional disorders in patients with non-tuberculous mycobacteriosis (NTM). Material and methods. A total of 178 patients with NTM caused by slowly growing species of NTM (M. avium, M. intracellulare, M. kansasii, M. xenopi, M. lentifl avum) were examined, including 145 women and 33 men aged 25 to 80 years. All patients underwent spirometry. Results. Ventilatory function disorders were identifi ed in 97 (54.5%) of the patients with NTM; among them, the majority—70 (39.3%) patients—exhibited obstructive disorders, while restrictive disorders were observed in 27 (15.2%) patients, which is half as frequent. The frequency and severity of lung function disorders were highest in patients with cavitary forms and lower in those with focal and bronchiectatic forms according to computed tomography (CT) of the lungs. The types of slowly growing mycobacteria did not have a signifi cant impact on the impairment of lung ventilatory function. Conclusion. Ventilatory function disorders were identifi ed in half of the patients with mycobacteriosis. Most frequently, ventilatory function impairment was observed in patients with cavitary forms. The high prevalence of functional disorders indicates the necessity of performing spirometry for all patients with NTM
About the Authors
M. I. Chushkin
Federal State Budgetary Scientifi c Institution Central Research Institute of Tuberculosis
Russian Federation
Russian Federation
Mihail I. Chushkin — Doctor of Medical Sciences, Leading Researcher at the Center for Diagnostics and Rehabilitation
Moscow
E. A. Shergina
Federal State Budgetary Scientifi c Institution Central Research Institute of Tuberculosis
Russian Federation
Russian Federation
Elena A. Shergina — Candidate of Medical Sciences, Head of the Department of Functional Diagnostics of the Center for Diagnosis and Rehabilitation of Respiratory Diseases
Moscow
A. D. Egorova
Federal State Budgetary Scientifi c Institution Central Research Institute of Tuberculosis
Russian Federation
Russian Federation
Anna D. Egorova — junior researcher at the Center for Diagnosis and Rehabilitation of Respiratory Diseases
Moscow
R. B. Amansakhedov
Federal State Budgetary Scientifi c Institution Central Research Institute of Tuberculosis
Russian Federation
Russian Federation
Rasulguly B. Amansakhedov — Doctor of Medical Sciences, Senior Researcher, Head of the Department of Radiation Diagnostics at the Center for Diagnosis and Rehabilitation of Respiratory Diseases
Moscow
N. I. Karpina
Federal State Budgetary Scientifi c Institution Central Research Institute of Tuberculosis
Russian Federation
Russian Federation
Natalia L. Karpina — Doctor of Medical Sciences, Deputy Director; Head of the Center for Diagnosis and Rehabilitation of Respiratory Diseases
Moscow
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Review
For citations:
Chushkin M.I., Shergina E.A., Egorova A.D., Amansakhedov R.B., Karpina N.I. Disorders of ventilatory function in patients with mycobacteriosis. Clinical Medicine (Russian Journal). 2025;103(3):202-207. (In Russ.) https://doi.org/10.30629/0023-2149-2025-103-3-202-207
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