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Autoimmune gastritis and Helicobacter pylori infection: how do these diseases relate to each other?
https://doi.org/10.30629/0023-2149-2024-102-9-10-723-726
Abstract
The article discusses the relationship between autoimmune gastritis and Helicobacter pylori (H. pylori) infection. The prevailing point of view in the literature is that Hpylori infection can act as a trigger factor, contributing to the development and progression of autoimmune gastritis due to the phenomenon of antigen mimicry. At the same time, there are publications on the protective effect of H. pylori infection in relation to the occurrence of autoimmune gastritis and the absence of a link between these diseases. Recent data indicate that the presence of Hpylori infection in patients with autoimmune gastritis contributes to the progression of atrophic changes of the mucous membrane and an increased risk of gastric cancer, which makes it justified to carry out eradication therapy in such cases, which allows to prevent the progression of the disease and the development of complications.
About the Authors
A. A. Sheptulin
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Arkadiy A. Sheptulin — Dr. Sci. (Med.), Professor of the Department of Internal Diseases Propedeutics, Gastroenterology and Hepatology, N.V. Sklifosovsky Institute of Clinical Medicine
Moscow
Yu. S. Rabotyagova
S.I. Georgievsky Medical Institute V.I. Vernadsky Crimean Federal University
Russian Federation
Russian Federation
Yuliya S. Rabotyagova — Cand. Sci. (Med.), Teaching Assistant at the Department of Therapy, Gastroenterology, Cardiology and General Medical Practice (Family Medicine), Faculty of Training of Highly Qualified Medical Personnel and Additional Professional Education
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Review
For citations:
Sheptulin A.A., Rabotyagova Yu.S. Autoimmune gastritis and Helicobacter pylori infection: how do these diseases relate to each other? Clinical Medicine (Russian Journal). 2024;102(9-10):723–726. (In Russ.) https://doi.org/10.30629/0023-2149-2024-102-9-10-723-726
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