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Diet therapy for obesity and bronchial asthma
https://doi.org/10.30629/0023-2149-2025-103-8-9-584-588
Abstract
Obesity and bronchial asthma are diseases that often accompany each other. Studies show that obesity increases the risk of developing bronchial asthma and makes it worse. In such cases, it is important to apply a comprehensive approach to treatment, including diet therapy. Personalized diet therapy can help patients not only reduce body fat, but also improve lung function and relieve asthma symptoms. In this article we will consider the basic principles of dietary therapy for such patients, as well as the relationship between diet, obesity and bronchial asthma.
Material and methods. Analysis of literature over the past 15 years using databases dataPubMed, eLIBRARYby key words: “obesity”, “bronchial asthma”, “systemic inflammation”, “diet”.
Results. Obesity has been shown to be accompanied by chronic inflammation, which can aggravate the inflammatory process in the airways in bronchial asthma. Studies show that diet therapy has a direct effect on inflammatory processes in the body. The diet, which contains a large amount of simple carbohydrates and saturated fats, plays an important role in causing systemic inflammation in obesity and worsening symptoms of bronchial asthma. On the other hand, studies show that a diet rich in antioxidants and polyunsaturated fatty acids can reduce inflammation in the body and improve control of asthma in obese patients.
Conclusion. A number of studies have been carried out on dietary therapy for patients with obesity and asthma, but their results are contradictory and require further consideration.
Supporting agencies: The source of funding is the federal budget. The publication was prepared as part of the fundamental research work of the Federal Research Centre for Nutrition, Biotechnology and Food Safety No. FGMF-2025-0003.
About the Authors
I. A. Lapik
Federal Research Centre for Nutrition, Biotechnology and Food Safety
Россия
Россия
Irina A. Lapik — Candidate of Medical Sciences, Research Scientist, Department of Nutritional Rehabilitation
Moscow
K. M. Gapparova
Federal Research Centre for Nutrition, Biotechnology and Food Safety
Россия
Россия
Kamilat M. Gapparova — Candidate of Medical Sciences, Head of the Department of Nutritional Rehabilitation
Moscow
References
1. Sharma V., Cowan D.C. Obesity, inflammation, and severe asthma: an update. Curr. Allergy Asthma Rep. 2021;21(12):46. DOI: 10.1007/s11882-021-01024-9
2. Miethe S., Karsonova A., Karaulov A., Renz H. Obesity and asthma. J. Allergy Clin. Immunol. 2020;146(4):685–693. DOI: 10.1016/j.jaci.2020.08.011
3. Bantulà M., Roca-Ferrer J., Arismendi E., Picado C. Asthma and obesity: two diseases on the rise and bridged by inflammation. J. Clin. Med. 2021;10(2):169. DOI: 10.3390/jcm10020169
4. Jevnikar Z., Östling J., Ax E., Calvén J. et al. Epithelial IL-6 transsignaling defines a new asthma phenotype with increased airway inflammation. J. Allergy Clin. Immunol. 2019;143(2):577–590. DOI: 10.1016/j.jaci.2018.05.026.
5. Engin A. The pathogenesis of obesity-associated adipose tissue inflammation. adv. Exp. Med. Biol. 2017;960:221–245. DOI: 10.1007/978-3-319-48382-5_9
6. Croce S., Avanzini M.A., Regalbuto C., Cordaro E. et al. Adipose tissue immunomodulation and Treg/Th17 imbalance in the impaired glucose metabolism of children with obesity. Children. 2021;8(7):554. DOI: 10.3390/children8070554
7. Qiu H., He Y., Ouyang F., Jiang P. et al. The role of regulatory t cells in pulmonary arterial hypertension. J. Am. Heart Assoc. 2019;8(23):e014201. DOI: 10.1161/JAHA.119.014201
8. Martinez-Sanchez M.E., Hiriart M., Alvarez-Buylla E.R. The CD4+ T cell regulatory network mediates inflammatory responses during acute hyperinsulinemia: a simulation study. BMC Syst. Biol. 2017;11(1):64. DOI: 10.1186/s12918-017-0436-y
9. Neves Miranda V.P.; Gouveia Peluzio, Rodrigues de Faria, Castro Franceschini et al. Inflammatory markers in relation to body composition, physical activity and assessment of nutritional status of the adolescents. Nutr. Hosp. 2015;31(5):1920–7. DOI: 10.3305/nh.2015.31.5.8586
10. Forno E., Weiner D.J., Mullen J., Sawicki G. et al. Obesity and airway dysanapsis in children with and without asthma. Am. J. Respir. Crit. Care Med. 2017;195(3):314–323. DOI: 10.1164/rccm.201605-1039OC
11. Wood L.G., Shivappa N., BerthonB.S., Gibson P.G. et al. Dietary inflammatory index is related to asthma risk, lung function and systemic inflammation in asthma. Clin. Exp. Allergy. 2015;45(1):83– 177. DOI: 10.1111/cea.12323
12. Koloverou Е., Panagiotakos D.B., Pitsavos С., Chrysohoou С. et al. Adherence to Mediterranean diet and 10-year incidence (2002-2012) of diabetes: correlations with inflammatory and oxidative stress biomarkers in the ATTICA cohort study. Diabetes Metab. Res. Rev. 2016;32(1):73–81. DOI: 10.1002/dmrr.2672
13. Seyedrezazadeh E., Moghaddam M.P., Ansarin K., Vafa M.R. et al. Fruit and vegetable intake and risk of wheezing and asthma: a systematic review and meta-analysis. Nutr. Rev. 2014;72:411–428. DOI: 10.1111/nure.12121.
14. Rice J.L., Romero К.М., Davila R.M.G., Tarazona С.М. et al. Association between adherence to the mediterranean diet and asthma in peruvian children. Lung. 2015;193(6):893–9. DOI: 10.1007/s00408-015-9792-9
15. Calatayud-Sáez F.M., Calatayud Moscoso Del Prado B, Gallego Fernández-Pacheco J.G. et al. Mediterranean diet and childhood asthma. Allergol Immunopathol (Madr). 2016;44:99–105. DOI: 10.1016/j.aller.2015.04.007
16. Schwingshackl L., Hoffmann G. Mediterranean dietary pattern, inflammation and endothelial function: a systematic review and meta-analysis of intervention trials. Nutr. Metab. Cardiovasc. Dis. 2014;24:929–939. DOI: 10.1016/j.numecd.2014.03.003
17. Lv, N.; Xiao, L.; Ma, J. Dietary pattern and asthma: a systematic review and meta-analysis. J. Asthma Allergy. 2014,7,105–121. DOI: 10.2147/JAA.S49960
18. Papamichael M.M., Itsiopoulos C., Susanto N.H., Erbas B. Does adherence to the mediterranean dietary pattern reduce asthma symptoms in children? A systematic review of observational studies. Public Health Nutr. 2017;20:2722–2734. DOI: 10.1017/S1368980017001823
19. Akcay A., Tamay Z., Hocaoglu A.B., Ergin A. et al. Risk factors affecting asthma prevalence in adolescents living in Istanbul, Turkey. Allergol. Immunopathol. (Madr.). 2014,42,449–458. DOI: 10.1016/j. aller.2013.05.005
20. Han Y-Y, Forno E., Brehm J.M. et al. Diet, interleukin-17, and childhood asthma in Puerto Ricans. Ann Allergy Asthma Immunol. 2015;115:288–293.e1. DOI: 10.1016/j.anai.2015.07.020
21. Lapik I.A., Gapparova K.M. Prospects of using antioxidants in the treatment of obesity and bronchial asthma. Collection of scientific articles. “Actual problems of science and technology. Innovatika». 2024;127–131. (In Russian).
22. Anitra C.С. Maggini S. Vitamin C and immune function. Nutrients. 2017;9(11):1211. DOI: 10.3390/nu9111211
23. Chen L., Chen С., Lin М., Li S. et al. Association between dietderived antioxidants and asthma: Insights from the NHANES survey 2003-2018 and Mendelian randomization analysis. Heart Lung. 2025;69:71–77. DOI: 10.1016/j.hrtlng.2024.09.014.
24. Guilleminault L., Williams E., Scott H., Berthon B. et al. Diet and asthma: is it time to adapt our message? Nutrients. 2017;9(11):1227. DOI: 10.3390/nu9111227
25. Bose S., Diette G.B., Woo H., Koehler K. et al. Vitamin D status modifies the response to indoor particulate matter in obese urban children with asthma. J. Allergy Clin. Immunol. 2019;7(6):1815– 1822.e2. DOI: 10.1016/j.jaip.2019.01.051
26. Batmaz S.B., Arıkoğlu T., Tamer L., Eskandari G. et al. Seasonal variation of asthma control, lung function tests and allergic inflammation in relation to vitamin D levels: a prospective annual study. Postepy Dermatol. Alergol. 2018;35(1):99–105. DOI: 10.5114/ada.2017.71421
27. Nassar M.F., Emam E.K., Allam M.F. Is There a Benefit of Vitamin D supplementation in deficient children and adolescents suffering from obesity? a meta-analysis. Glob. Pediatr. Health. 2021;27:8. DOI: 10.1177/2333794X211018352
28. Williamson A., Martineau A.R., Sheikh A., Jolliffe D. et al. Vitamin D for the management of asthma. Cochrane Database Syst. Rev. 2023;2(2):CD011511. DOI: 10.1002/14651858
29. Forno E., Bacharier L.B., Phipatanakul W., Guilbert T.W. et al. Effect of vitamin D3 supplementation on severe asthma exacerbations in children with asthma and low vitamin D levels: the VDKA randomized clinical trial. JAMA. 2020;324(8):752–760. DOI: 10.1001/jama.2020.12384
30. Li Q., Zhou Q., Zhang G., Tian X. et al. Vitamin D supplementation and allergic diseases during childhood: a systematic review and metaanalysis. Nutrients. 2022;14(19):3947. DOI: 10.3390/nu14193947
31. Fiamenghi V.I., Mello E.D. Vitamin D deficiency in children and adolescents with obesity: a meta-analysis. J. Pediatr. (Rio J.). 2021;97(3):273–279. DOI: 10.1016/j.jped.2020.08.006
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For citations:
Lapik I.A., Gapparova K.M. Diet therapy for obesity and bronchial asthma. Clinical Medicine (Russian Journal). 2025;103(8-9):584-588. (In Russ.) https://doi.org/10.30629/0023-2149-2025-103-8-9-584-588
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