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Disturbance of visuospatial and executive functions in patients with sleep apnea syndrome in the acute period of ischemic stroke
https://doi.org/10.30629/0023-2149-2025-103-3-196-201
Abstract
In patients with cerebral infarction (CI) and sleep apnea syndrome (SAS), neurocognitive disorders are a common symptom, which underscores the relevance of improving their early diagnosis and treatment. A prospective dynamic study was conducted on disorders of visual-constructive and executive skills (VCES) in 74 patients with SAS (main group) and 36 patients without SAS (comparison group) during the acute period of CI using route-building tests (RBT), cube copying tests (CCT), and clock drawing tests (CDT). It was found that patients with SAS exhibited more severe VCES disorders within the fi rst 72 hours of CI, primarily due to impaired performance on the CDT, and worse recovery after one month compared to patients without SAS (p < 0.05). The CDT showed good indicators for the early diagnosis of VCES disorders in patients with SAS and CI (AUC — 0.926 (95% CI 0.86–0.97; p < 0.0001), sensitivity — 100.0% (95% CI 84.6–100.0), specifi city — 85.23% (95% CI 76.1–91.90). In patients with severe SAS, the lowest scores for VCES, RBT, and CDT were established (p < 0.05), and moderate negative correlations were identifi ed between the CDT scores and the apnea-hypopnea index and desaturation index (p < 0.001). Among 20 patients receiving CPAP therapy, a positive dynamics in VCES scores was noted (p < 0.05), which was not observed in the subgroup without similar treatment, suggesting a positive eff ect of CPAP therapy on recovery in this cognitive domain
About the Author
E. V. Serebrova
Gomel State Medical University
Belarus
Belarus
Ekaterina V. Serebrova — Candidate of Medical Sciences, Senior Lecturer at the Department of Neurology and Neurosurgery with courses in Medical Rehabilitation, Psychiatry, Faculty of Advanced Training an
d Retraining
Gomel
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Review
For citations:
Serebrova E.V. Disturbance of visuospatial and executive functions in patients with sleep apnea syndrome in the acute period of ischemic stroke. Clinical Medicine (Russian Journal). 2025;103(3):196-201. (In Russ.) https://doi.org/10.30629/0023-2149-2025-103-3-196-201
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