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Fasting-dietary therapy and intermittent fasting as a unifi ed treatment and preventive strategy for age-associated human diseases

https://doi.org/10.30629/0023-2149-2025-103-3-169-180

Abstract

Changing dietary patterns plays a leading role, especially as a means against obesity and related metabolic diseases. Over the past decades, intermittent fasting regimens have gained popularity as an alternative to traditional weight loss strategies such as fasting-diet therapy and hypocaloric diets. Available literature suggests that intermittent fasting, taking into account the specifi c characteristics and needs of a person, can be recommended both as part of an individual program for weight loss and treatment of metabolic diseases, and after long cycles of fasting-dietary therapy in order to maintain positive treatment results in the long term. This review shows that the methods of complete fasting, low-calorie nutrition and intermittent fasting are eff ective non-pharmacological interventions for the correction of cardiometabolic disorders that contribute to an increase in life expectancy and suppression of oncogenesis and it is advisable to consider them within the framework of a unifi ed treatment and preventive strategy for age-associated human pathology

About the Authors

A. V. Esipov
National Medical Research Center for High Medical Technologies — A.A. Vishnevsky Central Military Clinical Hospital of the Ministry of Defense of Russia; Military Medical Academy named after S.M. Kirov (Branch, Moscow) of the Ministry of Defense of Russia
Russian Federation

Alexander V. Esipov — Doctor of Medical Sciences, Associate Professor, Head of the National Medical Research Center for High Medical Technologies; Professor of the Department of Surgery with a course in Oncology and Radiation Diagnostics

Krasnogorsk

Moscow



N. I. Gulyaev
National Medical Research Center for High Medical Technologies — A.A. Vishnevsky Central Military Clinical Hospital of the Ministry of Defense of Russia; Military Medical Academy named after S.M. Kirov (Branch, Moscow) of the Ministry of Defense of Russia; Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University) of the Ministry of Education and Science of Russia
Russian Federation

Nikolay I. Gulyaev — Doctor of Medical Sciences, Associate Professor, Head of the Cardiology Center of the National Medical Research Center for High Medical Technologies; Professor of the Department of Emergency Treatment; Lecturer at the Department of Hospital Therapy with courses in endocrinology, hematology and clinical laboratory diagnostics

Krasnogorsk

Moscow



A. P. Petko
National Medical Research Center for High Medical Technologies — A.A. Vishnevsky Central Military Clinical Hospital of the Ministry of Defense of Russia
Russian Federation

Anatoly P. Petko — Candidate of Medical Sciences, Head of the Center for Traditional Medicine and Rehabilitation Treatment

Krasnogorsk

 



A. A. Prokhorchik
National Medical Research Center for High Medical Technologies — A.A. Vishnevsky Central Military Clinical Hospital of the Ministry of Defense of Russia; Military Medical Academy named after S.M. Kirov (Branch, Moscow) of the Ministry of Defense of Russia
Russian Federation

Alexander A. Prokhorchik – Candidate of Medical Sciences, Chief Therapist; Lecturer at the Department of Emergency Treatment

Krasnogorsk

Moscow



D. A. Mironenko
National Medical Research Center for High Medical Technologies — A.A. Vishnevsky Central Military Clinical Hospital of the Ministry of Defense of Russia
Russian Federation

Dmitry A. Mironenko — Candidate of Medical Sciences, Head of the Therapeutic Department of the Center for Traditional Medicine and Rehabilitation Treatment

Krasnogorsk

 



B. G. Khudziev
National Medical Research Center for High Medical Technologies — A.A. Vishnevsky Central Military Clinical Hospital of the Ministry of Defense of Russia
Russian Federation

Batraz G. Khudziev — Candidate of Medical Sciences, general practitioner of the therapeutic department of the center of traditional medicine and rehabilitation treatment

Krasnogorsk

 



I. V. Kutenkova
National Medical Research Center for High Medical Technologies — A.A. Vishnevsky Central Military Clinical Hospital of the Ministry of Defense of Russia
Russian Federation

Irina V. Kutenkova — Internist at the therapeutic department of the center of traditional medicine and rehabilitation treatment

Krasnogorsk

 



L. E. Krivolap
Military Medical Academy named after S.M. Kirov (Branch, Moscow) of the Ministry of Defense of Russia
Russian Federation

Leonid E. Krivolap — Clinical resident of the department of emergency treatment

Moscow



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Review

For citations:


Esipov A.V., Gulyaev N.I., Petko A.P., Prokhorchik A.A., Mironenko D.A., Khudziev B.G., Kutenkova I.V., Krivolap L.E. Fasting-dietary therapy and intermittent fasting as a unifi ed treatment and preventive strategy for age-associated human diseases. Clinical Medicine (Russian Journal). 2025;103(3):169-180. (In Russ.) https://doi.org/10.30629/0023-2149-2025-103-3-169-180

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ISSN 0023-2149 (Print)
ISSN 2412-1339 (Online)