clinmedКлиническая медицинаClinical Medicine (Russian Journal)0023-21492412-1339ООО «Медицинское информационное агентство»10.30629/0023-2149-2024-102-11-12-908-911clinmed-995Research ArticleВ ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУGUIDELINES FOR PRACTITIONERSБольшие и гигантские язвы желудка: факторы риска и особенности дифференциальной диагностикиLarge and giant gastric ulcers: risk factors and features of differential diagnosisШептулинА. А.SheptulinA. A.

Шептулин Аркадий Александрович — д-р мед. наук, профессор кафедры пропедевтики внутренних болезней, гастроэнтерологии и гепатологии Института клинической медицины им. Н.В. Склифосовского

Москва

Arkadiy A. Sheptulin — Doctor of Medical Sciences, Professor of the Department of Internal Diseases Propedeutics, Gastroenterology and Hepatology, N.V. Sklifosovsky Institute of Clinical Medicine

Moscow

arkalshep@gmail.comРаботяговаЮ. С.RabotyagovaYu. S.

Работягова Юлия Сергеевна — канд. мед. наук, ассистент кафедры терапии, гастроэнтерологии, кардиологии и общей врачебной практики (семейной медицины) факультета последипломного образования

Симферополь

Yuliya S. Rabotyagova — Candidate of Medical Sciences, Teaching Assistant at the Department of Therapy, Gastroenterology, Cardiology and General Medical Practice (Family Medicine), Faculty of Training of Highly Qualified Medical Personnel and Additional Professional Education

Simferopol

ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)РоссияI.M.Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russia (Sechenov University)Russian FederationМедицинский институт им. С.И. Георгиевского ФГАОУ ВО «Крымский федеральный университет им. В.В. Вернадского» Минобрнауки РоссииРоссияMedical Institute named after S.I. Georgievsky V.V. Vernadsky Crimean Federal UniversityRussian Federation20241103202510211-12908911Copyright © Шептулин А.А., Работягова Ю.С., 20252025Шептулин А.А., Работягова Ю.С.Sheptulin A.A., Rabotyagova Y.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.clinmedjournal.com/jour/article/view/995

В представленной статье обсуждаются факторы риска возникновения больших и гигантских язв желудка (в частности, прием иммуносупрессантов, нестероидных противовоспалительных препаратов, инфекция), необходимость проведения дифференциальной диагностики между доброкачественными язвами и инфильтративно-язвенной формой рака желудка, а также другими его опухолевыми поражениями), особенности течения таких язв (склонность к кровотечениям, перфорации, пенетрации).

The presented article discusses the risk factors for occurrence of large and giant gastric ulcers (in particular, the use of immunosupressants, nonsteroidal anti-inflammatory drugs, infectious etiology), the need for differential diagnosis between benign ulcers and infiltrative ulcerative form of gastric cancer, as well as its other tumor lesions), the features of the course of such ulcers (tendency to bleeding, perforation, penetration).

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The authors declare that there are no conflicts of interest present.