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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinmed</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical Medicine (Russian Journal)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0023-2149</issn><issn pub-type="epub">2412-1339</issn><publisher><publisher-name>ООО «Медицинское информационное агентство»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/0023-2149-2020-98-7-503-507</article-id><article-id custom-type="elpub" pub-id-type="custom">clinmed-96</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Российские инновации лечения артериальной гипертонии в клинической практике — реальный путь к достижению успеха</article-title><trans-title-group xml:lang="en"><trans-title>Russian innovations in the treatment of arterial hypertension in clinical practice — a real way to achieve success</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7581-4138</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Боровкова</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Borovkova</surname><given-names>N. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Боровкова Наталья Юрьевна — доктор медицинских наук, профессор кафедры госпитальной терапии и общей врачебной практики им. В.Г. Вогралика</p><p>603950, Нижний Новгород</p></bio><bio xml:lang="en"><p>Natalia Yu. Borovkova — MD, PhD, DSc, Professor of the Department of hospital therapy and general medical practice named after V.G. Vogralik</p><p>603950, Nizhny Novgorod</p></bio><email xlink:type="simple">borovkov-nn@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Приволжский исследовательский медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Volga Research Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>31</day><month>12</month><year>2020</year></pub-date><volume>96</volume><issue>7</issue><fpage>503</fpage><lpage>507</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Боровкова Н.Ю., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Боровкова Н.Ю.</copyright-holder><copyright-holder xml:lang="en">Borovkova N.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.clinmedjournal.com/jour/article/view/96">https://www.clinmedjournal.com/jour/article/view/96</self-uri><abstract><p>Обзор посвящен знакомству широкого круга интернистов с новой фиксированной комбинацией рамиприла и индапамида (Консилар-Д24), созданной российскими учеными. Это первая оригинальная отечественная разработка для лечения артериальной гипертонии, которая с успехом производится первым российским резидентом особой экономической зоны — фармацевтическим заводом «ВЕРТЕКС» в Санкт-Петербурге. Преимуществом Консилара-Д24 является рациональное сочетание двух препаратов, имеющих не только антигипертензивный и органопротективный эффект, но и большую убедительную базу исследований их влияния на прогноз жизни пациентов с сердечно-сосудистыми заболеваниями: артериальной гипертонией, ишемической болезнью сердца, сердечной недостаточностью.</p></abstract><trans-abstract xml:lang="en"><p>The review is devoted to introducing a wide range of internists to the new fixed combination of ramipril and indapamide (Concealar-D24), created by Russian scientists. This is the first original domestic development for the treatment of arterial hypertension, which is successfully produced by the first Russian resident of the special economic zone, the pharmaceutical plant «VERTEX» in St. Petersburg. The advantage of Concealar-D24 is a rational combination of two drugs that have not only antihypertensive and organoprotective effects, but also a large convincing base of research on their impact on the prognosis of life in patients with cardiovascular diseases: arterial hypertension, coronary heart disease, heart failure.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертония</kwd><kwd>индапамид</kwd><kwd>рамиприл</kwd><kwd>фиксированная комбинация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial hypertension</kwd><kwd>indapamide</kwd><kwd>ramipril</kwd><kwd>fixed combination</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Williams B., Mancia G., Spiering W. et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension [published correction appears in J. 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