clinmedКлиническая медицинаClinical Medicine (Russian Journal)0023-21492412-1339ООО «Медицинское информационное агентство»10.30629/0023-2149-2020-98-7-485-490clinmed-93Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESПатогенетические основы венозных тромбоэмболических осложнений на фоне COVID-19Pathogenetic basis of venous thromboembolic complications as deuteropathies of COVID-19https://orcid.org/0000-0002-5930-3941ФедоровС. А.FedorovS. A.

Федоров Сергей Андреевич — кандидат медицинских наук, сердечно-сосудистый хирург

603950, Нижний Новгород, 

603005, Нижний Новгород

 

Sergey A. Fedorov — candidate of medical Sciences, cardiovascular surgeon

603950, Nizhny Novgorod,

603005, Nizhny Novgorod

Sergfedorov1991@yandex.ruМедведевА. П.MedvedevA. P.

603950, Нижний Новгород, 

603005, Нижний Новгород

603950, Nizhny Novgorod,

603005, Nizhny Novgorod

БоровковаН. Ю.BorovkovaN. Yu.

603005, Нижний Новгород

603005, Nizhny Novgorod

ТарановЕ. В.TaranovE. V.

603950, Нижний Новгород

603950, Nizhny Novgorod

ГБУЗ НО «Специализированная кардиохирургическая клиническая больница имени академика Б.А. Королева»; ФГБОУ ВО «Приволжский исследовательский медицинский университет» Министерства здравоохранения РФРоссияSpecialized Cardiosurgical Clinical Hospital named after Academician Korolev B.A.; Volga Research Medical University of the Ministry of Health of the Russian FederationRussian FederationФГБОУ ВО «Приволжский исследовательский медицинский университет» Министерства здравоохранения РФРоссияVolga Research Medical University of the Ministry of Health of the Russian FederationRussian FederationГБУЗ НО «Специализированная кардиохирургическая клиническая больница имени академика Б.А. Королева»РоссияSpecialized Cardiosurgical Clinical Hospital named after Academician Korolev B.A.Russian Federation202031122020967485490Copyright © Федоров С.А., Медведев А.П., Боровкова Н.Ю., Таранов Е.В., 20202020Федоров С.А., Медведев А.П., Боровкова Н.Ю., Таранов Е.В.Fedorov S.A., Medvedev A.P., Borovkova N.Y., Taranov E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.clinmedjournal.com/jour/article/view/93

В настоящее время можно отметить, что COVID-19 без преувеличения является наиболее серьезным вызовом международной системе практического здравоохранения в его новейшей истории. Крайне высокие показатели заболеваемости и летальности диктуют необходимость более детального изучения патогенетических аспектов развивающейся инфекционной катастрофы. Помимо респираторного дистресс-синдрома, синдрома системной воспалительной реакции, COVID-19 характеризуется поливалентными нарушениями механизмов системного гемостаза, что находит отражение в росте количества венозных тромбоэмболических осложнений в общей структуре заболеваемости и летальности. В приведенном литературном обзоре проведено обобщение информации, посвященной COVID-19-ассоциированной коагулопатии и ее влиянию на изменение клинической и эпидемиологической характеристик венозных тромбоэмболических осложнений.

Аt present, it can be noted without exaggeration that COVID-19 is the most serious challenge to the international system of practical health care in its recent history. Extremely high rates of morbidity and mortality dictate the need for a more detailed study of the pathogenetic aspects of the developing infectious disaster. In addition to respiratory distress syndrome, and systemic inflammatory response syndrome, COVID-19 is characterized by polyvalent disorders of the mechanisms of systemic hemostasis, which is reflected in the increase in the number of venous thromboembolic complications in the overall structure of morbidity and mortality. This literature review summarizes information on Covid-associated coagulopathy and its impact on changes in the clinical and epidemiological characteristics of venous thromboembolic complications.

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The authors declare that there are no conflicts of interest present.