<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinmed</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical Medicine (Russian Journal)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0023-2149</issn><issn pub-type="epub">2412-1339</issn><publisher><publisher-name>ООО «Медицинское информационное агентство»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/0023-2149-2024-102-5-6-441-446</article-id><article-id custom-type="elpub" pub-id-type="custom">clinmed-863</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЗАМЕТКИ И НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NOTES AND OBSERVATIONS FROM PRACTICE</subject></subj-group></article-categories><title-group><article-title>Лечение  варикозной болезни у пациента с протезированным митральным клапаном</article-title><trans-title-group xml:lang="en"><trans-title>Case report of varicose veins  treatment in patient with a prosthetic mitral valve</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4487-8061</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ибрагимов</surname><given-names>Д. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Ibragimov</surname><given-names>D. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ибрагимов Денис Радикович — канд. мед. наук, доцент кафедры факультетской хирургии; сосудистый хирург</p><p>Уфа</p></bio><bio xml:lang="en"><p>Denis R. Ibragimov — vascular surgeon; Candidate of Medical Sciences, Associate Professor of the Department of Faculty Surgery</p><p>Ufa</p></bio><email xlink:type="simple">ezikkk@icloud.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-7296-9552</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Минигалиева</surname><given-names>Э. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Minigalieva</surname><given-names>E. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минигалиева Эльвира Рашитовна — флеболог</p><p>Уфа</p></bio><bio xml:lang="en"><p>Elvira R. Minigalieva — phlebologist</p><p>Ufa</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хафизов</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Hafizov</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хафизов Азат Рафитович — канд. мед. наук, сердечно-сосудистый хирург, руководитель клиники</p><p>Уфа</p></bio><bio xml:lang="en"><p>Azat R. Hafizov — Candidate of Medical Sciences, Cardiovascular Surgeon, Head of the clinic</p><p>Ufa</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4144-3946</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олейник</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Oleinik</surname><given-names>B. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Олейник Богдан Александрович — канд. мед. наук, доцент кафедры госпитальной хирургии; сердечно-сосудистый хирург</p><p>Уфа</p></bio><bio xml:lang="en"><p>Bogdan A. Oleinik — cardiovascular surgeon; Candidate of Medical Sciences, Associate Professor of the Department of Hospital Surgery; </p><p>Ufa</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1919-0997</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мурасов</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Murasov</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мурасов Тимур Мансафович — сосудистый хирург, аспирант кафедры факультетской хирургии</p><p>Уфа</p></bio><bio xml:lang="en"><p>Timur M. Murasov — vascular surgeon, postgraduate student of the Department of Faculty Surgery</p><p>Ufa</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каипов</surname><given-names>А. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaipov</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каипов Артур Эрикович — сердечно-сосудистый хирург</p><p>Уфа</p></bio><bio xml:lang="en"><p>Artur E. Kaipov — cardiovascular surgeon</p><p>Ufa</p></bio><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ООО «Клиника современной флебологии»; ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России; ГБУЗ Республики Башкортостан Городская клиническая больница № 21</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinic of Modern Phlebology; Bashkir State Medical University of the Ministry of Health of Russia; City Clinical Hospital No. 21 Ufa</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО «Клиника современной флебологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinic of Modern Phlebology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ООО «Клиника современной флебологии»; ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinic of Modern Phlebology; Bashkir State Medical University of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБУЗ Республики Башкортостан Городская клиническая больница № 21</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital No. 21 Ufa</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ГБУЗ Республиканский кардиологический центр Минздрава Республики Башкортостан</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Republican Cardiology Center of the Ministry of Health of the Republic of Bashkortostan</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>08</day><month>11</month><year>2024</year></pub-date><volume>102</volume><issue>5-6</issue><fpage>441</fpage><lpage>446</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ибрагимов Д.Р., Минигалиева Э.Р., Хафизов А.Р., Олейник Б.А., Мурасов Т.М., Каипов А.Э., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Ибрагимов Д.Р., Минигалиева Э.Р., Хафизов А.Р., Олейник Б.А., Мурасов Т.М., Каипов А.Э.</copyright-holder><copyright-holder xml:lang="en">Ibragimov D.R., Minigalieva E.R., Hafizov A.R., Oleinik B.A., Murasov T.M., Kaipov A.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.clinmedjournal.com/jour/article/view/863">https://www.clinmedjournal.com/jour/article/view/863</self-uri><abstract><p>Данный клинический случай может представлять интерес в ситуациях, когда пациенту с варикозной болезнью нижних конечностей с сопутствующей патологией сердца (ревматической болезнью), находящемуся на длительной антикоагулянтной терапии, планируется проведение малого хирургического вмешательства. В своем клиническом наблюдении представили возможность проведения эндовенозной лазерной облитерации (ЭВЛО) на фоне приема варфарина без перехода на мост-терапию. У пациентки Г., 68 лет, с ревматическим комбинированным митральным по- роком сердца (протезирование митрального клапана (2019), постоянная форма фибрилляции предсердий) варикозная болезнь нижних конечностей. В анамнезе: острое нарушение мозгового кровообращения (19.01.2023). По данным ультразвукового дуплексного сканирования (УЗДС) вен нижних конечностей: несостоятельность клапана большой под- кожной вены слева. По результатам лабораторных анализов в коагулограмме наблюдалась гипокоагуляция. Средний риск по шкале HAS-BLED. По шкале Caprini очень высокий риск. Была проведена эндовенозная лазерная облитерация большой подкожной вены слева. На контрольных осмотрах — без признаков кровотечения из выполненных проколов. На УЗДС в динамике достигнута облитерация целевого ствола. Таким образом, возможно проведение ЭВЛО большой подкожной вены на фоне приема терапевтических доз варфарина без перехода на мост-терапию. Эндовенозная лазерная облитерация позволила с меньшими рисками кровотечения ее провести, а на фоне варфарина — снизить риск тромбообразования.</p></abstract><trans-abstract xml:lang="en"><p>This clinical case may be of interest in situations where a patient with varicose veins of the lower limbs and concomitant heart disease, who is on long-term anticoagulant therapy and is scheduled to undergo minor surgery, may present the possibility of endovenous laser ablation (EVLA) against the background of warfarin use. Patient, G., 68 years old, with rheumatic combined mitral valve disease (mitral valve replacement in 2019, permanent atrial fibrillation), also had varicose vein disease of the lower limbs. History included acute cerebrovascular accident (19.01.2023). Duplex Ultrasonography Screening (DUS) showed failure of the left great saphenous vein valve. Hypocoagulation was also observed in coagulogram and the risk of bleeding on HAS-BLED score was average. On Caprini score, the risk was very high. Endovenous laser ablation of the large saphenous vein on the left side was performed. During follow-up examinations, there were no signs of bleeding from puncture sites. The target trunk was obliterated in dynamics at DUS. Therefore, it is possible to carry out EVLA of a large subcutaneous vein while taking therapeutic doses of warfarin without switching to bridge therapy. Endovascular laser ablation allowed it to be done with less risk of bleeding and, against the background of taking warfarin, reduced the risk of thrombosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>варикозная болезнь</kwd><kwd>протезированный митральный клапан</kwd><kwd>варфарин</kwd><kwd>эндовенозная лазерная облитерация</kwd><kwd>ЭВЛО</kwd><kwd>мост-терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>varicose veins</kwd><kwd>prosthetic mitral valve</kwd><kwd>warfarin</kwd><kwd>endovenous laser ablation</kwd><kwd>EVLA</kwd><kwd>bridge therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Zolotukhin I.A., Seliverstov E.I., Shevtsov Y.N., Avakiants I.P., Nikishkov A.S., Tatarintsev A.M., Kirienko A.I. Prevalence and risk factors for chronic venous disease in the general russian population. Eur. J. Vasc. Endovasc. Surg. 2017;54(6):752–758.</mixed-citation><mixed-citation xml:lang="en">Zolotukhin I.A., Seliverstov E.I., Shevtsov Y.N., Avakiants I.P., Nikishkov A.S., Tatarintsev A.M., Kirienko A.I. Prevalence and risk factors for chronic venous disease in the general russian population. Eur. J. Vasc. Endovasc. Surg. 2017;54(6):752–758.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Rabe E., Guex J., Puskas A., Scuderi A., Fernandez Quesada F., Coordinators V. Epidemiology of chronic venous disorders in geographically diverse populations: results from the Vein Consult Program. Int. Angiol. 2012;2:105–115.</mixed-citation><mixed-citation xml:lang="en">Rabe E., Guex J., Puskas A., Scuderi A., Fernandez Quesada F., Coordinators V. Epidemiology of chronic venous disorders in geographically diverse populations: results from the Vein Consult Program. Int. Angiol. 2012;2:105–115.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Lunga B. and others. Decision-making in elderly patients with severe aortic stenosis: why are so many denied surgery? Eur. Heart J. 2005;26:2714–2720.</mixed-citation><mixed-citation xml:lang="en">Lunga B. and others. Decision-making in elderly patients with severe aortic stenosis: why are so many denied surgery? Eur. Heart J. 2005;26:2714–2720.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Hindricks G., Potpara T., Dagres N., et al.; ESC Scientific Document Group. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the diagnosis and management of atrial fi brillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Eur. Heart J. 2021;42(5):373–498. DOI: 10.1093/eurheartj/ehaa612</mixed-citation><mixed-citation xml:lang="en">Hindricks G., Potpara T., Dagres N., et al.; ESC Scientific Document Group. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the diagnosis and management of atrial fi brillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Eur. Heart J. 2021;42(5):373–498. DOI: 10.1093/eurheartj/ehaa612</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Форстер О.В., Царев О.А., Шварц Ю.Г. Взаимосвязь между варикозной болезнью нижних конечностей, выраженностью дисплазии соединительной ткани и фибрилляцией предсердий у пациентов с ишемической болезнью сердца. Ангиология и сосудистая хирургия. 2006;12(2):17–21.</mixed-citation><mixed-citation xml:lang="en">Forster O.V., Tsarev O.A., Shvarts Yu.G. The relationship between varicose veins of the lower extremities, the severity of connective tissue dysplasia and atrial fibrillation in patients with coronary heart disease. Angiologiya i sosudistaya khirurgiya. 2006;12(2):17–21. (In Russian).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Заболотских И.Б., Киров М.Ю., Божкова С.А. и др. Периоперационное ведение больных, получающих длительную антитромботическую терапию. Клинические рекомендации. 2013;25.</mixed-citation><mixed-citation xml:lang="en">Zabolotskikh I.B, Kirov M.Yu., Bozhkova S.A. i soavt. Perioperative management of patients receiving long-term antithrombotic therapy. Clinical recommendations. 2013;25. (In Russian). URL: http://www.far.org.ru/</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Camm A.J., Lip G.Y., De Caterina R., Savelieva I. et al. ESC Committee for Practice Guidelines (CPG). 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation. Developed with the special contribution of the European Heart Rhythm Association. European Heart Journal. 2012;33:2719–2747.</mixed-citation><mixed-citation xml:lang="en">Camm A.J., Lip G.Y., De Caterina R., Savelieva I. et al. ESC Committee for Practice Guidelines (CPG). 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation. Developed with the special contribution of the European Heart Rhythm Association. European Heart Journal. 2012;33:2719–2747.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Митральная регургитация. Клинические рекомендации Российской Федерации, подготовлены ассоциацией сердечно-сосудистых хирургов Министерства здравоохранения Российской Федерации. Москва, 2020:50</mixed-citation><mixed-citation xml:lang="en">Clinical recommendations of the Russian Federation, prepared by the Association of Cardiovascular Surgeons of the Ministry of Health of the Russian Federation. Moskva, 2020:50. (In Russian).</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Baumgartner H., Falk V., Bax J.J. et al. 2017 ESC/EACTS Guidelines for the management of valvular heart disease. Eur. Heart J. 2017;38(36):2739–91. DOI: 10.1093/eurheartj/ehx391</mixed-citation><mixed-citation xml:lang="en">Baumgartner H., Falk V., Bax J.J. et al. 2017 ESC/EACTS Guidelines for the management of valvular heart disease. Eur. Heart J. 2017;38(36):2739–91. DOI: 10.1093/eurheartj/ehx391</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Тимербулатов М.В., Мураcов Т.М., Ибрагимов Д.Р. Современный взгляд на диагностику и лечение тромбофлебита подкожных вен. Медицинский вестник Башкортостана. 2023;18(2) (104):74–79.</mixed-citation><mixed-citation xml:lang="en">Timerbulatov M.V., Murasov T.M., Ibragimov D.R. A modern view on the diagnosis and treatment of subcutaneous vein thrombophlebitis. Medical Bulletin of Bashkortostan. 2023;18(2) (104):74–79. (In Russian).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Gabriel V., Jimenez J.C., Alktaifi A., Lawrence P.F., O’Connell J., Derubertis B.G., Rigberg D.A., Gelabert H.A. Success of endovenous saphenous and perforator ablation in patients with symptomatic venous insufficiency receiving long-term warfarin therapy. Ann. Vasc. Surg. 2012;26(5):607–11. DOI: 10.1016/j.avsg.2011.10.019. Epub 2012 Apr 18. PMID: 22516240.</mixed-citation><mixed-citation xml:lang="en">Gabriel V., Jimenez J.C., Alktaifi A., Lawrence P.F., O’Connell J., Derubertis B.G., Rigberg D.A., Gelabert H.A. Success of endovenous saphenous and perforator ablation in patients with symptomatic venous insufficiency receiving long-term warfarin therapy. Ann. Vasc. Surg. 2012;26(5):607–11. DOI: 10.1016/j.avsg.2011.10.019. Epub 2012 Apr 18. PMID: 22516240.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Chang H., Sadek M., Barfield M.E., Rockman C.B., Maldonado T.S., Cayne N.S., Berland T.L., Garg K., Jacobowitz G.R. Direct oral anticoagulant agents might be safe for patients undergoing endovenous radiofrequency and laser ablation. Journal of vascular surgery. Venous and lymphatic disorders. 2023;11(1):25–30. DOI: 10.1016/j.jvsv.2022.05.011</mixed-citation><mixed-citation xml:lang="en">Chang H., Sadek M., Barfield M.E., Rockman C.B., Maldonado T.S., Cayne N.S., Berland T.L., Garg K., Jacobowitz G.R. Direct oral anticoagulant agents might be safe for patients undergoing endovenous radiofrequency and laser ablation. Journal of vascular surgery. Venous and lymphatic disorders. 2023;11(1):25–30. DOI: 10.1016/j.jvsv.2022.05.011</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Илюхин Е.А. Оставить, отменить или заменить? URL: https://actual-phlebology.ru/afpersons/ostavit-otmenit-ili-zamenit/</mixed-citation><mixed-citation xml:lang="en">Ilyukhin E.A. Leave, cancel or replace? (In Russian). [Electronic resource. URL: https://actual-phlebology.ru/afpersons/ostavit-otmenit-ili-zamenit/</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Westin G.G., Cayne N.S., Lee V., Ekstroem J., Yau P.O., Sadek M., Rockman C.B., Kabnick L.S., Berland T.L., Maldonado T.S., Jacobowitz G.R. Radiofrequency and laser vein ablation for patients receiving warfarin anticoagulation is safe, effective, and durable. J. Vasc. Surg. Venous Lymphat. Disord. 2020;8(4):610–616. DOI: 10.1016/j.jvsv.2019.11.013. Epub 2020 Jan 25. PMID: 31987758</mixed-citation><mixed-citation xml:lang="en">Westin G.G., Cayne N.S., Lee V., Ekstroem J., Yau P.O., Sadek M., Rockman C.B., Kabnick L.S., Berland T.L., Maldonado T.S., Jacobowitz G.R. Radiofrequency and laser vein ablation for patients receiving warfarin anticoagulation is safe, effective, and durable. J. Vasc. Surg. Venous Lymphat. Disord. 2020;8(4):610–616. DOI: 10.1016/j.jvsv.2019.11.013. Epub 2020 Jan 25. PMID: 31987758</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
