clinmedКлиническая медицинаClinical Medicine (Russian Journal)0023-21492412-1339ООО «Медицинское информационное агентство»10.30629/0023-2149-2023-101-6-265-274clinmed-560Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESПостковидные нейрокогнитивные расстройстваPost-COVID neurocognitive disordersСапроненковаО. А.SapronenkovaO. A.

Сапроненкова Ольга Алексеевна— доцент кафедры терапии неотложных состояний.

107392, Москва

Olga A. Sapronenkova.

107392, Moscow

https://orcid.org/0000-0002-8717-7372ШироковЕ. А.ShirokovE. A.

Широков Евгений Алексеевич— профессор кафедры терапии неотложных состояний.

107392, Москва

Evgeny A. Shirokov.

107392, Moscow

Evg-747747@yandex.ruФилиал ФГБВОУ ВО Военно-медицинская академия им. С.М. Кирова в г. МосквеРоссияMilitary Medical Academy named after S.M. Kirov (Moscow Branch) of the Ministry of Defense of RussiaRussian Federation2023200720231016265274Copyright © Сапроненкова О.А., Широков Е.А., 20232023Сапроненкова О.А., Широков Е.А.Sapronenkova O.A., Shirokov E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.clinmedjournal.com/jour/article/view/560

В статье рассматриваются причины и механизмы развития когнитивных нарушений у больных, перенесших COVID-19. Обзор научных публикаций последних лет показал, что нарушение функции центральной нервной системы является одним из ключевых признаков коронавирусной инфекции. Постковидный неврологический синдром отмечается у большинства больных. Авторы обобщили данные о проникновении вирусов в структуры головного мозга и изучили ведущие механизмы повреждения нервной системы, связанные с вирусной инфекцией. Предложены перспективные направления профилактики и лечения нейрокогнитивных нарушений, связанных с перенесенной коронавирусной инфекцией.

The article discusses the causes and mechanisms of cognitive disorders in patients who have recovered from COVID-19. A review of scientific publications in recent years has shown that the impairment of central nervous system function is one of the key features of coronavirus infection. Post-COVID neurological syndrome is observed in most patients. The authors have summarized data on the penetration of viruses into brain structures and studied the leading mechanisms of nervous system damage associated with viral infection. Promising directions for the prevention and treatment of neurocognitive disorders associated with past coronavirus infection are proposed.

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The authors declare that there are no conflicts of interest present.