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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinmed</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical Medicine (Russian Journal)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0023-2149</issn><issn pub-type="epub">2412-1339</issn><publisher><publisher-name>ООО «Медицинское информационное агентство»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/0023-2149-2021-99-11-12-632-636</article-id><article-id custom-type="elpub" pub-id-type="custom">clinmed-320</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Риск кардиологических и цереброваскулярных осложнений у пациентов с сопутствующими сердечно-сосудистыми заболеваниями, переболевших COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>The risk of cardiac and cerebrovascular complications in patients with concomitant cardiovascular diseases who have had COVID-19</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5063-5571</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клячина</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Klyachina</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клячина Екатерина Сергеевна  — ассистент кафедры факультетской терапии, эндокринологии, аллергологии и иммунологии  </p><p>620028, Екатеринбург</p></bio><bio xml:lang="en"><p>Klyachina Ekaterina S.</p><p>620028, Yekaterinburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0705-6651</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смоленская</surname><given-names>О. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Smolenskaya</surname><given-names>O. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Смоленская Ольга Георгиевна — д-р мед. наук, профессор, заведующая кафедрой факультетской терапии,эндокринологии, аллергологии и иммунологии</p><p>620028, Екатеринбург</p></bio><bio xml:lang="en"><p>Smolenskaya Olga G.</p><p>620028, Yekaterinburg</p></bio><email xlink:type="simple">o.smolenskaya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Уральский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural State Medical University of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>04</day><month>03</month><year>2022</year></pub-date><volume>99</volume><issue>11-12</issue><fpage>632</fpage><lpage>636</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Клячина Е.С., Смоленская О.Г., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Клячина Е.С., Смоленская О.Г.</copyright-holder><copyright-holder xml:lang="en">Klyachina E.S., Smolenskaya O.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.clinmedjournal.com/jour/article/view/320">https://www.clinmedjournal.com/jour/article/view/320</self-uri><abstract><p>Во время пандемии, вызванной вирусом SARS-CoV-2, особой группой риска являются пациенты с сердечно-сосудистыми заболеваниями (ССЗ), которые часто встречаются в популяции. Осложнения со стороны сердечно-сосудистой системы после COVID-19 могут возникать в разные периоды заболевания. В представленной работе описаны сердечно-сосудистые осложнения у пациентов после выздоровления.</p><p>Цель исследования — выявить частоту развития новых ССЗ и осложнений имеющейся кардиологической патологии у пациентов, переболевших COVID-19.</p><sec><title>Материал и методы</title><p>Материал и методы. Проведено ретроспективное, обсервационное исследование, включающее 370 пациентов. Со всеми пациентами проведены телефонные консультации в течение 6 мес. после выписки из инфекционного госпиталя. При выявлении новых ССЗ, осложнений или ухудшении течения имеющихся заболеваний, были проведены очные визиты.</p></sec><sec><title>Результаты</title><p>Результаты. Среди исследуемых 370 пациентов сопутствующие ССЗ зарегистрированы у 249 (67,29%) человек, у 121 (32,71%) пациента не было сердечно-сосудистой патологии в анамнезе. У пациентов с сопутствующими ССЗ в течение первых 6 мес. после выписки из инфекционного госпиталя зарегистрировано 25 (10,04%) новых сердечнососудистых событий, что достоверно чаще, чем у больных, не имеющих ССЗ в анамнезе (n = 1; 0,83%). Количество вышеописанных событий чаще наблюдалось в первые 3 мес. после выписки, что является статистически значимым (р ˂ 0,05). Среди ухудшений основных ССЗ наиболее часто наблюдалась дестабилизация АД (n = 67; 27,2%), что, возможно, связано с повышенным уровнем тревожности пациентов. Также замечено, что новые ССЗ, как и ухудшение уже имеющихся, развивались в том числе вследствие не оказанной своевременно специализированной кардиологической медицинской помощи, что, вероятно, и привело к нежелательным событиям из-за невозможности вовремя скорректировать факторы риска ССЗ.</p></sec><sec><title>Выводы</title><p>Выводы. У пациентов, имеющих сопутствующие ССЗ, после перенесенного COVID-19, в отличие от пациентов без ССЗ в анамнезе, достоверно выше риск развития новых сердечно-сосудистых событий. Наиболее пристальное внимание заслуживают больные с ССЗ в течение первых 3 мес. после выписки из инфекционного госпиталя.</p></sec></abstract><trans-abstract xml:lang="en"><p>During the pandemic caused by the SARS-CoV-2 virus, patients with cardiovascular diseases (CVD), which are often found in the population, are a special risk group. Cardiovascular complications after COVID-19 can occur at diff erent periods of the disease. This research describes cardiovascular complications in patients after recovery.</p><p>The aim of the study was to identify the incidence of new CVD and complications of existing cardiac pathology in patients who recovered from COVID-19.</p><sec><title>Material and methods</title><p>Material and methods. A retrospective, observational study including 370 patients was conducted. All patients underwent telephone consultations within 6 months after the infectious diseases hospital discharge. When new CVDs, complications or anabasis were identifi ed, follow-up visits were initiated.</p></sec><sec><title>Results</title><p>Results. Among 370 patients under the study, concomitant CVD was registered in 249 (67.29%) people, 121 (32.71%) patients had no case history of cardiovascular pathology. In patients with concomitant CVD during the fi rst 6 months after the infectious diseases hospital discharge, 25 (10.04%) new cardiovascular events were registered, which is signifi cantly more frequent than in patients without case history of CVD (n = 1; 0.83%). The number of events described above was more often observed in the fi rst 3 months after discharge, which is statistically signifi cant (p ˂ 0.05). BP destabilization was most often observed (n = 67; 27.2%) as anabasis, which may be associated with an increased level of anxiety in patients. It was also noted that new CVDs, as well as anabasis, developed because of the timely specialized cardiological medical care absence, which probably led to undesirable events due to inability to correct CVD risk factors in time.</p></sec><sec><title>Conclusions</title><p>Conclusions. In patients with concomitant CVD, who have had COVID-19, in contrast to patients without case history of CVD, the risk of developing new cardiovascular events is signifi cantly higher. Patients with CVD deserve the closest attention during the fi rst 3 months after discharge from the infectious diseases hospital.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>коронавирусная инфекция</kwd><kwd>COVID-19</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>кардиологические осложнения</kwd><kwd>SARS-CoV-2</kwd></kwd-group><kwd-group xml:lang="en"><kwd>coronavirus infection</kwd><kwd>COVID-19</kwd><kwd>cardiovascular diseases</kwd><kwd>cardiac complications</kwd><kwd>SARS-CoV-2</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Silverio A., Di Maio M., Ciccarelli M., Carrizzo A. et al. Timing of national lockdown and mortality in COVID-19: The Italian experience. International Journal of Infectious Diseases. 2020; 100:193–195.</mixed-citation><mixed-citation xml:lang="en">Silverio A., Di Maio M., Ciccarelli M., Carrizzo A. et al. 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