clinmedКлиническая медицинаClinical Medicine (Russian Journal)0023-21492412-1339ООО «Медицинское информационное агентство»10.30629/0023-2149-2021-99-7-8-420-428clinmed-283Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESСтероидная глаукомаSteroid glaucomahttps://orcid.org/0000-0002-3821-689XНагорноваЗ. М.NagornovaA. M.

Нагорнова З.М., ассистент кафедры оториноларингологии и офтальмологии

153012, Иваново

153012, Ivanovo

https://orcid.org/0000-0002-4583-6050СелезневА. В.SeleznеvA. V.

Селезнев А.В., канд. мед. наук, доцент кафедры оториноларингологии и офтальмологии

153012, Иваново

153012, Ivanovo

https://orcid.org/0000-0003-2348-4880БулахИ. А.BulakhI. A.

Булах И.А., врач-офтальмолог

153021, Иваново

 153021, Ivanovo

БрежневА. Ю.BrezhnevA. Yu.

Брежнев А.Ю., канд. мед. наук, доцент кафедры офтальмологии

305041, Курск

305041, Kursk

https://orcid.org/0000-0001-9606-0566КуроедовА. В.KuroyedovA. V.

Куроедов А.В., д-р мед. наук, начальник отделения, профессор кафедры офтальмологии

117997, Москва; 107014, Москва

117997, Moscow; 107014, Moscow

ФГБОУ ВО «Ивановская государственная медицинская академия» Минздрава РоссииРоссияIvanovo State Medical AcademyRussian FederationООО «МЦ Ивастрамед»РоссияLLC IvastramedRussian FederationФГБОУ ВО «Курский государственный медицинский университет» Минздрава РоссииРоссияKursk State Medical UniversityRussian FederationФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России; ФКУ «Центральный военный клинический госпиталь им. П.В. Мандрыка» Минобороны РоссииРоссияPirogov Russian National Research Medical University of the Ministry of Health of Russia; FKI Central Military Clinical Hospital named after Mandrykа P.V. of the Ministry of Defense of RussiaRussian Federation202104012022997-8420428Copyright © Нагорнова З.М., Селезнев А.В., Булах И.А., Брежнев А.Ю., Куроедов А.В., 20222022Нагорнова З.М., Селезнев А.В., Булах И.А., Брежнев А.Ю., Куроедов А.В.Nagornova A.M., Seleznеv A.V., Bulakh I.A., Brezhnev A.Y., Kuroyedov A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.clinmedjournal.com/jour/article/view/283

Глюкокортикостероиды широко применяются как в общеклинической, так и в офтальмологической практике. Однако их неоправданное использование недопустимо, а назначения должны строго контролироваться и требуют мониторинга уровня внутриглазного давления, так как одними из установленных побочных эффектов препаратов этого ряда являются повышение уровня офтальмотонуса и развитие глаукомной оптиконейропатии. В данном обзоре рассмотрен патогенез повышения уровня внутриглазного давления на фоне приема различных форм глюкокортикостероидов, описано время и продолжительность их офтальмогипертензивного действия. Подробно изучены имеющиеся данные об особенностях клинической картины стероидной глаукомы в зависимости от путей их введения. Описана тактика лечения пациентов с офтальмогипертензией или установленным диагнозом стероидной глаукомы.

Glucocorticosteroids are widely used in clinical and ophthalmic practice, but their unjustifi ed and uncontrollable use is unacceptable. Prescription of steroids has to be controlled strictly and the level of intraocular pressure must be diagnosed, because one of the signifi cant side eff ect of steroids is increased intraocular pressure level and, as a result, the development of glaucomatous optic neuropathy. This review deals with the pathogenesis of an increase in the level of intraocular pressure against various forms of glucocorticosteroids intake, describes the time and duration of their ocular-hypertensive eff ect. The available data on the features of the clinical picture of steroid glaucoma, depending on the routes of their entry, have been studied in detail. The tactics of treating patients with ocular hypertension or a proven case of steroid glaucoma are described.

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The authors declare that there are no conflicts of interest present.