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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinmed</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical Medicine (Russian Journal)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0023-2149</issn><issn pub-type="epub">2412-1339</issn><publisher><publisher-name>ООО «Медицинское информационное агентство»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/0023-2149-2020-98-2-153-156</article-id><article-id custom-type="elpub" pub-id-type="custom">clinmed-26</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЗАМЕТКИ И НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NOTES AND OBSERVATIONS FROM PRACTICE</subject></subj-group></article-categories><title-group><article-title>Ревматическая полимиалгия на фоне аденокарциномы простаты</article-title><trans-title-group xml:lang="en"><trans-title>Rheumatic polymyalgia on the background of prostate adenocarcinoma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4890-0847</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Королев</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Korolev</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630060, Новосибирск</p></bio><bio xml:lang="en"><p>630060, Novosibirsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6275-2924</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Летягина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Letyagina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630060, Новосибирск</p></bio><bio xml:lang="en"><p>630060, Novosibirsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0900-1600</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Банщикова</surname><given-names>Н. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Banshchikova</surname><given-names>N. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Банщикова Надежда Евгеньевна — врач-ревматолог, мл. науч. сотр. лаборатории патологии соединительной ткани</p><p>630060, Новосибирск</p></bio><bio xml:lang="en"/><email xlink:type="simple">nadib1990@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт клинической и экспериментальной лимфологии — филиал ФГБНУ «Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук» (НИИКЭЛ — филиал ИЦиГ СО РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Clinical and Experimental Lymphology — branch of the Federal Research Center Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>15</day><month>07</month><year>2020</year></pub-date><volume>98</volume><issue>2</issue><fpage>153</fpage><lpage>156</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Королев М.А., Летягина Е.А., Банщикова Н.Е., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Королев М.А., Летягина Е.А., Банщикова Н.Е.</copyright-holder><copyright-holder xml:lang="en">Korolev M.A., Letyagina E.A., Banshchikova N.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.clinmedjournal.com/jour/article/view/26">https://www.clinmedjournal.com/jour/article/view/26</self-uri><abstract><p>Паранеопластические синдромы (ПНС) диагностируются у 7–10% больных со злокачественными новообразованиями. Наиболее часто ПНС сопровождают бронхогенный рак легкого, рак молочной железы, нефрокарциному, рак яичников, предстательной железы, матки. Неопластический процесс может стать причиной как острой, так и хронической воспалительной реакции с патологическими изменениями соединительной ткани и сосудов в различных органах и системах. Диагностика паранеопластических синдромов нередко трудна. Вместе с тем определенные признаки, выявляемые у больных с ревматическими масками неоплазм, должны вызвать у врача-ревматолога онкологическую настороженность. К числу таких признаков относятся возникновение ревматической патологии в нетипичном возрасте; отсутствие полового диморфизма, типичного для многих ревматических заболеваний; несоответствие тяжести клинических проявлений общему состоянию больного и показателям активности воспалительного процесса; отсутствие отдельных клинических и лабораторных признаков, типичных для того или иного ревматического заболевания; появление новых, не свойственных данному ревматическому заболеванию симптомов. В качестве клинического примера, иллюстрирующего сложность диагностики, в данной статье описан клинический случай ревматической полимиалгии на фоне аденокарциномы предстательной железы у мужчины 74 лет.</p></abstract><trans-abstract xml:lang="en"><p>Paraneoplastic syndromes diagnosed in 7–10% of patients with malignancies in general. PNS accompany bronchogenic lung, breast, ovarian, prostate, kidney and uterus cancers most often. Neoplastic process can cause by both the acute and the chronic inflammatory response with pathologic changes of the connective tissues and vascular in various organs and systems. Diagnosis of paraneoplastic syndromes is difficult often. However, some signs should cause of rheumatologist the oncologic alertness, which were found in patients with rheumatic masks of neoplasms. Among such signs include: the occurrence of rheumatic diseases in an abnormal age; the absence of sexual dimorphism, is typical of many rheumatic diseases; the difference between the severity of clinical manifestations and the general condition of the patient with an index of inflammatory activity; the absence of separate clinical and laboratory signs typical one or another rheumatic disease; the appearance of new symptoms, not characteristic of the rheumatic diseases. As a clinical example to illustrate the difficulty of diagnosis, this article describes a clinical case of adenocarcinoma of the prostate in 74-year-old men presenting as polymyalgia rheumatica.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ревматическая полимиалгия</kwd><kwd>паранеопластический синдром</kwd><kwd>аденокарцинома простаты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>polymyalgia rheumatic</kwd><kwd>paraneoplastic syndrome</kwd><kwd>adenocarcinoma of the prostate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bojinca V., Janta I. Rheumatic diseases and malignancies. Maedica (Buchar). 2012;7(4):364–71.</mixed-citation><mixed-citation xml:lang="en">Bojinca V., Janta I. Rheumatic diseases and malignancies. 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