clinmedКлиническая медицинаClinical Medicine (Russian Journal)0023-21492412-1339ООО «Медицинское информационное агентство»10.30629/0023-2149-2021-99-3-234-236clinmed-221Research ArticleДИСКУССИЯDISCUSSIONДвунаправленные связи при коморбидных заболеванияхBidirectional associations in comorbid diseaseshttps://orcid.org/0000-0003-2206-8922БеляловФ. И.BelyalovF. I.

Белялов Фарид Исмагильевич - д-р мед. наук, профессор кафедры геронтологии, гериатрии и клинической фармакологии

664079, Иркутск

Farid I. Belyalov - MD, PhD, DSc, professor of the Gerontology, Geriatry, and Clinical Pharmacology Department

Irkutsk, 664079

fbelyalov@mail.ruИркутская государственная медицинская академия последипломного образования - филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава РоссииРоссияIrkutsk State Medical Academy of Postgraduate Education — Branch of the Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian FederationRussian Federation202115092021993234236Copyright © Белялов Ф.И., 20212021Белялов Ф.И.Belyalov F.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.clinmedjournal.com/jour/article/view/221

Двунаправленные связи при коморбидных заболеванияхУвеличение количества пациентов с коморбидными заболеваниями и полифармакотерапией требует поиска оптимальных подходов к лечению. В статье обсуждаются клинические аспекты двусторонних связей между заболеваниями, которые проявляются повышением частоты, тяжести, ухудшением прогноза сочетанных болезней. Общие факторы риска и патофизиологические механизмы заболеваний могут послужить основой для разработки оптимального лечения пациентов c коморбидностью.

The increasing number of patients with comorbid diseases with polypharmacotherapy requires the search for optimal approaches to the treatment. The article discusses clinical aspects of bilateral connection manifested by an increase in frequency, severity and worsening prognosis of comorbid diseases. Common risk factors and pathophysiological mechanisms of diseases can serve as a basis for the development of optimal treatment of patients with comorbidity.

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The authors declare that there are no conflicts of interest present.