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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinmed</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical Medicine (Russian Journal)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0023-2149</issn><issn pub-type="epub">2412-1339</issn><publisher><publisher-name>ООО «Медицинское информационное агентство»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/0023-2149-2021-99-1-58-62</article-id><article-id custom-type="elpub" pub-id-type="custom">clinmed-181</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GUIDELINES FOR PRACTITIONERS</subject></subj-group></article-categories><title-group><article-title>Инфаркт миокарда в молодом возрасте: факторы риска, клиническая картина, особенности ведения на госпитальном этапе</article-title><trans-title-group xml:lang="en"><trans-title>Myocardial infarction at a young age: risk factors, clinical presentation, features of management in the hospital</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>390026, Рязань</p></bio><bio xml:lang="en"><p>390026, Ryazan</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6141-8994</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Переверзева</surname><given-names>К. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Pereverzeva</surname><given-names>K. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Переверзева Кристина Геннадьевна — кандидат медицинских наук, доцент кафедры госпитальной терапии с курсом медико-социальной экспертизы</p><p>390026, Рязань</p></bio><bio xml:lang="en"><p>Pereverzeva Kristina G.— MD, PhD, Associate Professor, Chair of Hospital Therapy</p><p>390026, Ryazan</p></bio><email xlink:type="simple">pereverzevakg@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4041-5676</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бояков</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Boyakov</surname><given-names>D. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>390026, Рязань</p></bio><bio xml:lang="en"><p>390026, Ryazan</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2625-0035</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хазов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chuchunov</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>390026, Рязань</p></bio><bio xml:lang="en"><p>390026, Ryazan</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0651-7268</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чучунов</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Khazov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>390026, Рязань</p></bio><bio xml:lang="en"><p>390026, Ryazan</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ ВО «Рязанский государственный медицинский университет имени академика И.П. Павлова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ryazan State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>04</day><month>06</month><year>2021</year></pub-date><volume>99</volume><issue>1</issue><fpage>58</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Денисов В.И., Переверзева К.Г., Бояков Д.Ю., Хазов Д.А., Чучунов А.Д., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Денисов В.И., Переверзева К.Г., Бояков Д.Ю., Хазов Д.А., Чучунов А.Д.</copyright-holder><copyright-holder xml:lang="en">Denisov V.I., Pereverzeva K.G., Boyakov D.Y., Chuchunov A.D., Khazov D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.clinmedjournal.com/jour/article/view/181">https://www.clinmedjournal.com/jour/article/view/181</self-uri><abstract><sec><title>Цель</title><p>Цель: изучить факторы риска, особенности клиники, диагностики и лечения пациентов с инфарктом миокарда (ИМ) молодого возраста (≤ 44 лет).</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование включено 189 пациентов, перенесших ИМ в период с 1 января 2015 г. по 31 декабря 2019 г. в возрасте ≤ 44 лет, из них 92,1% мужчин. Медиана возраста всех пациентов — 41,2 (37,3; 43,6) года.</p></sec><sec><title>Результаты</title><p>Результаты. Наиболее часто встречающимися факторами риска (ФР) развития ИМ являлись: курение в 77,8% случаев, гипертоническая болезнь в 73,5%, отягощенная наследственность в 49,2%, ожирение в 39,7% и сахарный диабет в 10,6% случаев. У 87,8% пациентов на электрокардиограмме (ЭКГ) — подъем сегмента ST, из них у 4,2% пациентов проведена только тромболитическая терапия, у 30,7% — тромболитическая терапия с последующей коронароангиографией (КАГ), у 54,2% — КАГ с намерением выполнить первичное чрескожное коронарное вмешательство (ЧКВ). Чрескожная транслюминальная коронарная ангиопластика и/или эндопротезирование коронарных артерий проведены у 76,5% пациентов. У 12,2% пациентов — острый коронарный синдром без подъема сегмента ST (ЭКГ), из них у 95,7% пациентов была проведена КАГ с намерением выполнить ЧКВ. Чрескожная транслюминальная коронарная ангиопластика и/или эндопротезирование коронарных артерий проведены у 73,9% пациентов без подъема сегмента ST на ЭКГ. Частота назначения бета-адреноблокаторов составила 95,2% (178 из 187), ингибиторов ангиотензинпревращающего фермента и сартанов — 95,2% (178 из 187), статинов — 99,5% (188 из 189), двойной антиагрегантной терапии — 99,5% (188 из 189), антагонистов минералокортикоидных рецепторов при фракции выброса левого желудочка ≤ 40% — 28,6% (2 из 7).</p></sec><sec><title>Заключение</title><p>Заключение. Проведенное исследование затрагивает актуальную тему ведения молодых пациентов с ИМ. Оно акцентирует внимание на ФР, клинической и ангиографической картине и вторичной профилактике.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim: to study the risk factors, clinical peculiarities, diagnosis and treatment of young patients with myocardial infarction (≤ 44 years).</p></sec><sec><title>Material and methods</title><p>Material and methods. The research included 189 patients, who had MI in the period from January 1, 2015 to December 31, 2019 at the age of ≤ 44; 92.1% of patients were men. The average age of all patients was 41,2 (37.3; 43.6).</p></sec><sec><title>Results</title><p>Results. Most frequent risk factors for the development of MI were: smoking — in 77.8%, essential hypertension — in 73.5%, burdened inheritance — in 49.2%, obesity — in 39.7% and pancreatic diabetes — in 10.6% of all cases. ST segment elevation was registered on the electrocardiogram in 87,8% of patients; 4.2% of them had only thrombolytic therapy; thrombolytic therapy was followed by coronarography with the intention of performing percutaneous coronary intervention (PCI) in 30.7% of cases; coronarography with the intention of performing primary PCI was applied to 54.2% of patients. PCI was performed in 76.5% of patients. 12.2% of patients had acute coronary syndrome without ST-segment elevation, and 95.7% of them had coronarography with the intention of performing percutaneous coronary intervention. PCI was performed in 73.9% of patients. Assignment frequency of beta-adrenergic blocking agent prescription was 95,2% (178 out of 187), аngiotensin-convertingenzyme inhibitors and sartans — 95.2% (178 out of 187), statins — 99.5% (188 of 189), dual antiplatelet therapy — 99.5% (188 out of 189), mineral corticoid receptor antagonists with ejection fraction of left ventricle of heart ≤ 40% — 28.6% (2 of 7).</p></sec><sec><title>Conclusion</title><p>Conclusion. The conducted research aims at the discussion of the vital topic of young patients with myocardial infarction management. It focuses on risk factors, clinical and angiographic presentation, and secondary prevention.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>инфаркт миокарда</kwd><kwd>молодой возраст</kwd><kwd>чрескожное коронарное вмешательство</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myocardial infarction</kwd><kwd>young age</kwd><kwd>percutaneous coronary intervention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Townsend N., Nichols M., Scarborough P. et al. Cardiovascular disease in Europe — epidemiological update 2015. Eur. Heart. J. 2015;36(40):2696–705. DOI: 10.1093/eurheartj/ehv428</mixed-citation><mixed-citation xml:lang="en">Townsend N., Nichols M., Scarborough P. et al. Cardiovascular disease in Europe — epidemiological update 2015. Eur. Heart. J. 2015;36(40):2696–705. 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