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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinmed</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical Medicine (Russian Journal)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0023-2149</issn><issn pub-type="epub">2412-1339</issn><publisher><publisher-name>ООО «Медицинское информационное агентство»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/0023-2149-2020-98-8-600-605</article-id><article-id custom-type="elpub" pub-id-type="custom">clinmed-122</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Хирургия инфекционного эндокардита (40-летний опыт лечения)</article-title><trans-title-group xml:lang="en"><trans-title>Surgery of infectious endocarditis (40 years of treatment experience)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7473-7572</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шевченко</surname><given-names>Ю. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Shevchenko</surname><given-names>Yu. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шевченко Юрий Леонидович — д-р мед. наук, проф., академик РАН, Президент </p><p>105203, Москва</p></bio><bio xml:lang="en"><p>Yuriy L. Shevchenko — MD. PhD, DSc. prof.Academician of the Russian Academy of Sciences, President </p><p>105203, Moscow</p></bio><email xlink:type="simple">yur.leon@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медико-хирургический центр им. Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical and Surgical Center named after N.I. Pirogov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>07</day><month>02</month><year>2021</year></pub-date><volume>98</volume><issue>8</issue><fpage>600</fpage><lpage>605</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шевченко Ю.Л., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Шевченко Ю.Л.</copyright-holder><copyright-holder xml:lang="en">Shevchenko Y.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.clinmedjournal.com/jour/article/view/122">https://www.clinmedjournal.com/jour/article/view/122</self-uri><abstract><p>На опыте хирургического лечения 3700 больных инфекционным эндокардитом рассмотрены вопросы этиологии, патогенеза, особенностей клиники и диагностики внутрисердечной инфекции. Представлены принципы хирургических вмешательств при различных формах инфекционного эндокардита, а также при наиболее тяжелых его вариантах, сопровождающихся деструкцией внутрисердечных структур и поражением других органов. Проанализированы непосредственные и отдаленные результаты лечения и возможности их улучшения.</p></abstract><trans-abstract xml:lang="en"><p>The issues of etiology, pathogenesis, clinical features and diagnosis of intracardiac infection are considered on the basis of the experience of surgical treatment of 3700 patients with infectious endocarditis. The principles of surgical interventions for various forms of infectious endocarditis, as well as for its most severe variants, accompanied by destruction of intracardiac structures and damage to other organs, are presented. The immediate and long- term results o f treatment and opportunities for their improvement are analyzed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инфекционный эндокардит</kwd><kwd>хирургическое лечение</kwd><kwd>внутрисердечная инфекция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>infectious endocarditis</kwd><kwd>surgical treatment</kwd><kwd>intracardiac infection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Tornos P., Iung B., Permanyer-Miralda G., Baron G., Delahaye F., Gohlke-Bärwolf Ch., Butchart E.G., Ravaud P., Vahanian A. Infective endocarditis in Europe: lessons from the Euro heart survey. Heart. 2005;91(5):571–5. PubMed PMID: 15831635; PubMed Central PMCID: PMC1768869.</mixed-citation><mixed-citation xml:lang="en">Tornos P., Iung B., Permanyer-Miralda G., Baron G., Delahaye F., Gohlke-Bärwolf Ch., Butchart E.G., Ravaud P., Vahanian A. 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