References

clinmed

Клиническая медицина

Clinical Medicine (Russian Journal)

0023-21492412-1339

ООО «Медицинское информационное агентство»

10.30629/0023-2149-2025-103-5-333-338

clinmed-1138

Research Article

ОБЗОРЫ И ЛЕКЦИИ

REVIEWS AND LECTURES

Распространенность и факторы риска инсульта у больных ВИЧ-инфекцией

Prevalence and risk factors of stroke in patients with HIV infection

https://orcid.org/0000-0003-0632-6653

Юсупов

Ф. А.

Yusupov

F. A.

Фуркат Абдулахатович Юсупов – д-р мед. наук, профессор медицинского факультета

Ош

Furkat A.Yusupov – Doctor of Medical Sciences, Professor of the Faculty of Medicine

Osh

https://orcid.org/0000-0003-4839-1306

Ыдырысов

И. Т.

Ydyrysov

I. T.

Исматилла Токтосунович Ыдырысов – д-р мед. наук, профессор медицинского факультета

Ош

Ismatilla T. Ydyrysov – Doctor of Medical Sciences, Professor of the Faculty of Medicine

Osh

https://orcid.org/0000-0002-4179-9205

Юлдашев

А. А.

Yuldashev

A. A.

Акмал Акбарович Юлдашев – аспирант кафедры неврологии, нейрохирургии и психиатрии медицинского факультета

Ош

Akmal A. Yuldashev – postgraduate student of the Department of Neurology, Neurosurgery and Psychiatry of the Medical Faculty

Osh

akmal.yuldashev.2017@list.ru

Ошский государственный университетКыргызстанOsh State UniversityKyrgyzstan

2025

22092025

1035333338

2025

Юсупов Ф.А., Ыдырысов И.Т., Юлдашев А.А.

Yusupov F.A., Ydyrysov I.T., Yuldashev A.A.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.clinmedjournal.com/jour/article/view/1138

Инсульт у больных ВИЧинфекцией представляет собой важную медицинскую проблему, связанную с рядом специфических факторов риска и повышенной распространенностью по сравнению с общей популяцией. В последние десятилетия улучшение антиретровирусной терапии значительно увеличило продолжительность жизни пациентов с ВИЧ, что привело к росту хронических заболеваний, включая сердечнососудистые и цереброваскулярные. Распространенность инсульта у пациентов с ВИЧ значительно выше, что связано с многофакторной природой инсульта, включающей как традиционные факторы риска, так и специфические для ВИЧ механизмы. К факторам риска инсульта у больных ВИЧ относятся возраст, длительность инфекции, высокий уровень вирусной нагрузки, низкий уровень CD4клеток, наличие сопутствующих заболеваний, таких как гипертония и сахарный диабет, курение. Кроме того, повышать риск могут определенные виды антиретровирусной терапии. Для снижения вероятности развития инсульта у пациентов с ВИЧ необходим комплексный подход, включающий контроль над вирусной нагрузкой, регулярный мониторинг сердечнососудистого здоровья, изменение образа жизни и коррекцию факторов риска.

Цель: провести обзор современных данных литературы, посвященной инсульту при ВИЧинфекции, его распространенности и факторам риска.

Stroke in patients with HIV infection is a significant medical problem associated with a number of specific risk factors and increased prevalence compared to the general population. In recent decades, improvements in antiretroviral therapy have significantly increased the life expectancy of HIV patients, which has led to an increase in chronic diseases, including cardiovascular and cerebrovascular. The prevalence of stroke in HIV patients is significantly higher, which is due to the multifactorial nature of stroke, including both HIVspecific mechanisms and traditional risk factors. Risk factors for stroke in HIV patients include age, duration of infection, high viral load, low CD4 cell count, the presence of concomitant diseases such as hypertension and diabetes mellitus, and smoking. In addition, certain types of antiretroviral therapy may increase the risk. To reduce the risk of stroke in HIV patients, a comprehensive approach is needed, including control of viral load, regular monitoring of cardiovascular health, lifestyle changes and correction of risk factors such as hypertension, hyperlipidemia and diabetes. Objective: to review the current literature on the problem of stroke in HIV infection in terms of prevalence and risk factors.

инсультВИЧинфекцияраспространенностьфакторы риска

strokeHIV infectionprevalencerisk factors

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The authors declare that there are no conflicts of interest present.