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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinmed</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical Medicine (Russian Journal)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0023-2149</issn><issn pub-type="epub">2412-1339</issn><publisher><publisher-name>ООО «Медицинское информационное агентство»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/0023-2149-2025-103-3-229-232</article-id><article-id custom-type="elpub" pub-id-type="custom">clinmed-1100</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЗАМЕТКИ И НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NOTES AND OBSERVATIONS FROM PRACTICE</subject></subj-group></article-categories><title-group><article-title>Дифференциальная диагностика лимфаденопатии: лимфома в практике врача-терапевта</article-title><trans-title-group xml:lang="en"><trans-title>Diff erential diagnostics of lymphadenopathy: lymphoma in the clinical practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0208-2401</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шаленкова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shalenkova</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шаленкова Мария Алексеевна — д-р мед. наук, профессор, консультант</p><p>Нижний Новгород</p></bio><bio xml:lang="en"><p>Maria A. Shalenkova — Doctor of Medical Sciences, Professor, consultant</p><p>Nizhniy Novgorod</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-6816-6699</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Манюкова</surname><given-names>Э. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Manyukova</surname><given-names>E. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Манюкова Эльвира Тахировна — канд. мед. наук, консультант</p><p>Нижний Новгород</p></bio><bio xml:lang="en"><p>Elvira T. Manyukova — Candidate of Medical Sciences, consultant</p><p>Nizhniy Novgorod</p></bio><email xlink:type="simple">elwira.manyukova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-2793-5431</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муравьева</surname><given-names>Л. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Muravyova</surname><given-names>L. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Муравьева Людмила Петровна — канд. мед. наук, доцент, врач гематологического отделения</p><p>Нижний Новгород</p></bio><bio xml:lang="en"><p>Lyudmila P. Muravyova — Can didate of Medical Sciences, Associate Professor, Doctor of the Hematology Department</p><p>Nizhniy Novgorod</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-2793-5431</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муравьев</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Muravyov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Муравьев Владимир Вячеславович — канд. мед. наук, заведующий гематологическим отделением</p><p>Нижний Новгород</p></bio><bio xml:lang="en"><p>Vladimir V. Muravyov — Candidate of Medical Sciences, Head of the Hematology Department</p><p>Nizhniy Novgorod</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-3493-1872</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасова</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasova</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тарасова Елена Геннадьевна — врач гематологического отделения</p><p>Нижний Новгород</p></bio><bio xml:lang="en"><p>Elena G. Tarasova — doctor at the Hematology Department</p><p>Nizhniy Novgorod</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ НО «Городская клиническая больница №38 Нижегородского района Нижнего Новгорода»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical Hospital No. 38</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ НО «Городская клиническая больница №12 Сормовского района Нижнего Новгорода»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical Hospital No. 12</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>03</day><month>07</month><year>2025</year></pub-date><volume>103</volume><issue>3</issue><fpage>229</fpage><lpage>232</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шаленкова М.А., Манюкова Э.Т., Муравьева Л.П., Муравьев В.В., Тарасова Е.Г., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Шаленкова М.А., Манюкова Э.Т., Муравьева Л.П., Муравьев В.В., Тарасова Е.Г.</copyright-holder><copyright-holder xml:lang="en">Shalenkova M.A., Manyukova E.T., Muravyova L.P., Muravyov V.V., Tarasova E.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.clinmedjournal.com/jour/article/view/1100">https://www.clinmedjournal.com/jour/article/view/1100</self-uri><abstract><p>Врачу любой специальности приходится сталкиваться с лимфаденопатией (ЛАП), являющейся симптомом различных заболеваний. Дифференциальный диагноз ЛАП при лимфопролиферативных заболеваниях имеет большое значение в силу высокой смертности при данной патологии. В статье представлен клинический случай, описывающий трудности дифференциальной диагностики ЛАП и верификации Т-клеточной лимфомы</p></abstract><trans-abstract xml:lang="en"><p>A doctor of any specialty has to deal with lymphadenopathy (LAP), which is a symptom of various diseases. The diff erential diagnosis of LAP in lymphoproliferative diseases is important due to the high mortality rate in this pathology. The article presents a clinical case describing the diffi culties of diff erential diagnosis of LAP and verifi cation of T-cell lymphoma</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лимфаденопатия</kwd><kwd>лимфома</kwd><kwd>лимфопролиферативное заболевание</kwd><kwd>болезнь Лайма</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lymphadenopathy</kwd><kwd>lymphoma</kwd><kwd>lymphoproliferative disease</kwd><kwd>Lyme disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Maini R., Nagalli S. Lymphadenopathy. [Updated 2022 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. 2024 Jan. URL: https://www.ncbi.nlm.nih.gov/books/NBK558918/</mixed-citation><mixed-citation xml:lang="en">Maini R., Nagalli S. Lymphadenopathy. Updated 2022 Aug 8. In: StatPearls Internet. Treasure Island (FL): StatPearls Publishing. 2024 Jan. 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