<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinmed</journal-id><journal-title-group><journal-title xml:lang="ru">Клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Clinical Medicine (Russian Journal)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0023-2149</issn><issn pub-type="epub">2412-1339</issn><publisher><publisher-name>ООО «Медицинское информационное агентство»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/0023-2149-2020-98-7-536-542</article-id><article-id custom-type="elpub" pub-id-type="custom">clinmed-101</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GUIDELINES FOR PRACTITIONERS</subject></subj-group></article-categories><title-group><article-title>Периодическая болезнь (семейная средиземноморская лихорадка) у жителей Дагестана</article-title><trans-title-group xml:lang="en"><trans-title>Cases of Periodic Disease (Familial Mediterranean fever) among Dagestan Republic population</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эседов</surname><given-names>Э. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Esedov</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>367000, Махачкала</p></bio><bio xml:lang="en"><p>Makhachkala, 367000</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абасова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Abasova</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Абасова Альбина Серажудинова — кандидат медицинских наук, доцент кафедры госпитальной терапии</p><p>367000, Махачкала</p><p> </p></bio><bio xml:lang="en"><p>Albina S. Abasova — MD. PhD, Assotiate Professor of the Department of Hospital Therapy № 2</p><p>Makhachkala, 367000</p></bio><email xlink:type="simple">albinadgma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Меджидова</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Medzhidova</surname><given-names>R. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>367000, Махачкала</p></bio><bio xml:lang="en"><p>Makhachkala, 367000</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Биячуева</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Biyachueva</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>367000, Махачкала</p></bio><bio xml:lang="en"><p>Makhachkala, 367000</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ «Дагестанский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Dagestan State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>31</day><month>12</month><year>2020</year></pub-date><volume>96</volume><issue>7</issue><fpage>536</fpage><lpage>542</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Эседов Э.М., Абасова А.С., Меджидова Р.А., Биячуева Л.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Эседов Э.М., Абасова А.С., Меджидова Р.А., Биячуева Л.А.</copyright-holder><copyright-holder xml:lang="en">Esedov E.M., Abasova A.S., Medzhidova R.A., Biyachueva L.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.clinmedjournal.com/jour/article/view/101">https://www.clinmedjournal.com/jour/article/view/101</self-uri><abstract><p>В статье представлен краткий обзор современных представлений о периодической болезни (семейной средиземноморской лихорадке). Приведены рекомендации по диагностике и своевременному лечению колхицином как протекции развития амилоидоза почек на основе анализа собственного клинического материала.</p></abstract><trans-abstract xml:lang="en"><p>The article represents a brief overwiev of current understanding concerning Periodic Disease (Familial Mediterranean fever). There are some recommendations for diagnostics and modern treatment with the use of Colchicine, as a protection from kidney amyloidosis development. Materials are based on the analysis of our own clinical data.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>периодическая болезнь</kwd><kwd>семейная средиземноморская лихорадка</kwd><kwd>пирин</kwd><kwd>колхицин</kwd><kwd>мутация гена МЕFV (Mеditerranian FeVer)</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Periodic Disease</kwd><kwd>Familial Mediterranean fever</kwd><kwd>pyrine</kwd><kwd>colchicine</kwd><kwd>mutation of MEFV gene</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ben-Zvi I., Livneh A. Chronic inflammation in FMF: markers, risk factors, outcomes and therapy. Nat. Rev. Rheumatol. 2011;7(2):105– 112.</mixed-citation><mixed-citation xml:lang="en">Ben-Zvi I., Livneh A. Chronic inflammation in FMF: markers, risk factors, outcomes and therapy. Nat. Rev. Rheumatol. 2011;7(2):105– 112.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Onen F. Familial Mediterranean fever. Rheumatol. Int. 2006;26(6):489–946.</mixed-citation><mixed-citation xml:lang="en">Onen F. Familial Mediterranean fever. Rheumatol. Int. 2006;26(6):489–946.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Janeway T.C., Mosenthal H. Unusual paroxysmal syndrome, probably allied to recurrent vomiting, with a study of nitrogen metabolism. Trans. Assoc. Am. Physicians. 1908;23:504–518.</mixed-citation><mixed-citation xml:lang="en">Janeway T.C., Mosenthal H. Unusual paroxysmal syndrome, probably allied to recurrent vomiting, with a study of nitrogen metabolism. Trans. Assoc. Am. Physicians. 1908;23:504–518.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Siegal S. Benign paroxysmal peritonitis. Ann. Intern. Med. 1945;13:1–22.</mixed-citation><mixed-citation xml:lang="en">Siegal S. Benign paroxysmal peritonitis. Ann. Intern. Med. 1945;13:1–22.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Mamou H., Cattan R. La maladie periodique. Sem. Hop. Paris 1952;28:1062–1070.</mixed-citation><mixed-citation xml:lang="en">Mamou H., Cattan R. La maladie periodique. Sem. Hop. Paris 1952;28:1062–1070.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Heller H., Sohar E., Sherf L. Familial Mediterranean fever. AMA Arch. Intern. Med. 1958;102(1):50–71.</mixed-citation><mixed-citation xml:lang="en">Heller H., Sohar E., Sherf L. Familial Mediterranean fever. AMA Arch. Intern. Med. 1958;102(1):50–71.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Goldfinger S.E. Colchicine for familial Mediterranean fever. N. Engl. J. Med. 1972;287(25):1302.</mixed-citation><mixed-citation xml:lang="en">Goldfinger S.E. Colchicine for familial Mediterranean fever. N. Engl. J. Med. 1972;287(25):1302.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">The International FMF Consortium. Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. Cell. 1997;90(4):797–807.</mixed-citation><mixed-citation xml:lang="en">The International FMF Consortium. Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. Cell. 1997;90(4):797–807.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">French FMF Consortium. A candidate gene for familial Mediterranean fever. Nat. Genet. 1997;17(1):25–31.</mixed-citation><mixed-citation xml:lang="en">French FMF Consortium. A candidate gene for familial Mediterranean fever. Nat. Genet. 1997;17(1):25–31.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Fonnesu C., Cerquaglia C., Giovinale M. et al. Familial Medi terra nean Fever: a review for clinical management. Joint Bone Spine 2009;76(3):227–233.</mixed-citation><mixed-citation xml:lang="en">Fonnesu C., Cerquaglia C., Giovinale M. et al. Familial Medi terra nean Fever: a review for clinical management. Joint Bone Spine 2009;76(3):227–233.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Onen F, Sumer H, Turkay S, Akyurek O, Tunca M, Ozdogan H. Increased frequency of familial Mediterranean fever in Central Anatolia, Turkey. Clin. Exp. Rheumatol. 2004;22(34):31–33.</mixed-citation><mixed-citation xml:lang="en">Onen F, Sumer H, Turkay S, Akyurek O, Tunca M, Ozdogan H. Increased frequency of familial Mediterranean fever in Central Anatolia, Turkey. Clin. Exp. Rheumatol. 2004;22(34):31–33.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Cobankara V., Fidan G., Turk T., Zencir M., Colakoglu M., Ozen S. The prevalence of familial Mediterranean fever in the Turkish province of Denizli: a field study with a zero patient design. Clin. Exp. Rheumatol. 2004;22(34):27–30.</mixed-citation><mixed-citation xml:lang="en">Cobankara V., Fidan G., Turk T., Zencir M., Colakoglu M., Ozen S. The prevalence of familial Mediterranean fever in the Turkish province of Denizli: a field study with a zero patient design. Clin. Exp. Rheumatol. 2004;22(34):27–30.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Kisacik B., Yildirim B., Tasliyurt T. et al. Increased frequency of familial Mediterranean fever in northern Turkey: a population-based study. Rheumatol. Int. 2009;29(11):1307–1309.</mixed-citation><mixed-citation xml:lang="en">Kisacik B., Yildirim B., Tasliyurt T. et al. Increased frequency of familial Mediterranean fever in northern Turkey: a population-based study. Rheumatol. Int. 2009;29(11):1307–1309.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Lidar M., Yaqubov M., Zaks N., Ben-Horin S., Langevitz P., Livneh A. The prodrome: a prominent yet overlooked pre-attack manifestation of familial Mediterranean fever. J. Rheumatol. 2006;33(6):1089–1092.</mixed-citation><mixed-citation xml:lang="en">Lidar M., Yaqubov M., Zaks N., Ben-Horin S., Langevitz P., Livneh A. The prodrome: a prominent yet overlooked pre-attack manifestation of familial Mediterranean fever. J. Rheumatol. 2006;33(6):1089–1092.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Cobankara V., Balkarli A. Ailesel Akdeniz Ateşi. Pam. Med. J. 2011;4(2):86–98.</mixed-citation><mixed-citation xml:lang="en">Cobankara V., Balkarli A. Ailesel Akdeniz Ateşi. Pam. Med. J. 2011;4(2):86–98.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Ben-Chetrit E., Levy M. Familial Mediterranean fever. Lancet 1998;351(9103):659–664.</mixed-citation><mixed-citation xml:lang="en">Ben-Chetrit E., Levy M. Familial Mediterranean fever. Lancet 1998;351(9103):659–664.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Demirturk L., Ozel A.M., Cekem K., Yazgan Y., Gultepe M. Coexistence of Helicobacter pylori infection in patients with Familial Mediterranean Fever (FMF) and the effect of Helicobacter pylori on the frequency and severity of FMF attacks. Dig. Liver Dis. 2005;37(3):153–158.</mixed-citation><mixed-citation xml:lang="en">Demirturk L., Ozel A.M., Cekem K., Yazgan Y., Gultepe M. Coexistence of Helicobacter pylori infection in patients with Familial Mediterranean Fever (FMF) and the effect of Helicobacter pylori on the frequency and severity of FMF attacks. Dig. Liver Dis. 2005;37(3):153–158.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Ozel AM, Demirturk L, Aydogdu A, et al. Effect of Helicobacter pylori infection and eradication therapy on interleukin-6 levels in patients with Familial Mediterranean Fever. Int. J. Clin. Pract. 2008;62(5):754–761.</mixed-citation><mixed-citation xml:lang="en">Ozel AM, Demirturk L, Aydogdu A, et al. Effect of Helicobacter pylori infection and eradication therapy on interleukin-6 levels in patients with Familial Mediterranean Fever. Int. J. Clin. Pract. 2008;62(5):754–761.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Ben-Chetrit E., Ben-Chetrit A. Familial Mediterranean fever and menstruation. BJOG 2001;108(4):403–407.</mixed-citation><mixed-citation xml:lang="en">Ben-Chetrit E., Ben-Chetrit A. Familial Mediterranean fever and menstruation. BJOG 2001;108(4):403–407.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Toubi E., Gershoni-Baruch R., Kuten A. Cisplatin treatment triggers familial Mediterranean fever attacks. Tumori. 2003;89(1):80–81.</mixed-citation><mixed-citation xml:lang="en">Toubi E., Gershoni-Baruch R., Kuten A. Cisplatin treatment triggers familial Mediterranean fever attacks. Tumori. 2003;89(1):80–81.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Shohat M, Halpern GJ. Familial Mediterranean fever — a review. Genet. Med. 2011;13(6):487–498.</mixed-citation><mixed-citation xml:lang="en">Shohat M, Halpern GJ. Familial Mediterranean fever — a review. Genet. Med. 2011;13(6):487–498.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Ben-Chetrit E, Levy M. Familial Mediterranean fever. Lancet 1998;351(9103):659–664.</mixed-citation><mixed-citation xml:lang="en">Ben-Chetrit E, Levy M. Familial Mediterranean fever. Lancet 1998;351(9103):659–664.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Soylu A, Kasap B, Turkmen M, Saylam GS, Kavukcu S. Febrile myalgia syndrome in familial Mediterranean fever. J. Clin. Rheumatol. 2006;12(2):93–96.</mixed-citation><mixed-citation xml:lang="en">Soylu A, Kasap B, Turkmen M, Saylam GS, Kavukcu S. Febrile myalgia syndrome in familial Mediterranean fever. J. Clin. Rheumatol. 2006;12(2):93–96.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Салугина С.О., Федоров Е.С. Опыт диагностики, лечения и курации пациентов с криопирин-ассоциированными периодическими синдромами в ревматологической практике. Педиатрия. 2018;97(3):103–109.</mixed-citation><mixed-citation xml:lang="en">Salugina S.O., Fedorov E.S. Experience of diagnostics, treatment and curation of patients with cryopyrin-associated periodic syndromes in rheumatological practice. Pediatrics. 2018;97(3):103–109. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Рамеев В.В., Богданова М.В., Федоров Е.С., Салугина С.О., Симонян А.Х., Моисеев С.В. Козловская Л.В., Мухин Н.А. Современные подходы к лечению колхицинрезистентной периодической болезни. Клиническая фармакология и терапия. 2017;26(3):59–68.</mixed-citation><mixed-citation xml:lang="en">Rameev V.V., Bogdanova M.V., Fedorov E.S., Salugina S.O., Simonyan A.Kh., Moiseev S.V. Kozlovskaya L.V., Mukhin N.A. Modern approaches to the treatment of colchicineresistant periodic disease. Clinical pharmacology and therapy. 2017;26(3):59–68. (in Russian)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
